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和其潜在的抗糖尿病特性的生物活性成分:综述。

Bioactive Components of and Their Potential Antidiabetic Properties: A Review.

机构信息

Nutrition, Metabolism and Cardiovascular Research Centre, Institute for Medical Research, National Institutes of Health, Ministry of Health, Malaysia, No.1, Jalan Setia Murni U13/52, Seksyen U13 Setia Alam, Shah Alam 40170, Malaysia.

出版信息

Molecules. 2021 May 20;26(10):3042. doi: 10.3390/molecules26103042.

DOI:10.3390/molecules26103042
PMID:34065175
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8161164/
Abstract

The utilization of therapeutic plants is expanding around the globe, coupled with the tremendous expansion of alternative medicine and growing demand in health treatment. Plants are applied in pharmaceuticals to preserve and expand health-physically, mentally and as well as to treat particular health conditions and afflictions. There are more than 600 families of plants identified so far. Among the plants that are often studied for their health benefit include the genus of in the mint family, Lamiaceae. This review aims to determine the bioactive components of and their potential as antidiabetic agents. The search was conducted using three databases (PubMed, EMBASE and Scopus), and all relevant articles that are freely available in the English language were extracted within 10 years (2011-2021). spp. comprises many biologically active components that can be divided into monoterpenes, diterpenes, triterpenes, and phenolic components, but only a few of these have been studied in-depth for their health benefit claims. The most commonly studied bioactive component was salvianolic acids. Interestingly, is undoubtedly the most widely studied species in terms of its effectiveness as an antidiabetic agent. In conclusion, we hope that this review stimulates more studies on bioactive components from medicinal plants, not only on their potential as antidiabetic agents but also for other possible health benefits.

摘要

药用植物的利用在全球范围内不断扩大,伴随着替代医学的巨大扩张和对医疗保健的需求增长。植物被应用于药物中,以保持和增进身体健康——身体上、精神上,并用于治疗特定的健康状况和疾病。迄今为止,已经确定了 600 多种植物科属。在经常因其健康益处而被研究的植物中,包括唇形科薄荷属的植物。本综述旨在确定 和其作为抗糖尿病药物的潜力的生物活性成分。使用三个数据库(PubMed、EMBASE 和 Scopus)进行了检索,并提取了 10 年内(2011-2021 年)所有可在英文免费获取的相关文章。 spp. 包含许多生物活性成分,可分为单萜、二萜、三萜和酚类成分,但只有少数这些成分因其健康益处声称而被深入研究。最常研究的生物活性成分是丹酚酸。有趣的是,就其作为抗糖尿病剂的有效性而言, 无疑是研究最广泛的 种。总之,我们希望这篇综述能激发更多关于药用植物生物活性成分的研究,不仅是它们作为抗糖尿病药物的潜力,还有其他可能的健康益处。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/70ac/8161164/aa9327b8530d/molecules-26-03042-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/70ac/8161164/c804474118fa/molecules-26-03042-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/70ac/8161164/292400846133/molecules-26-03042-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/70ac/8161164/a7c692801e86/molecules-26-03042-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/70ac/8161164/aa9327b8530d/molecules-26-03042-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/70ac/8161164/c804474118fa/molecules-26-03042-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/70ac/8161164/292400846133/molecules-26-03042-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/70ac/8161164/a7c692801e86/molecules-26-03042-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/70ac/8161164/aa9327b8530d/molecules-26-03042-g004.jpg

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