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面向临床生物传感的半导体界面研究进展

Recent Progress on Semiconductor-Interface Facing Clinical Biosensing.

机构信息

School of Engineering, University of Manchester, Manchester M13 9PL, UK.

Chemistry Department, Oakland University, Rochester, MI 48309, USA.

出版信息

Sensors (Basel). 2021 May 16;21(10):3467. doi: 10.3390/s21103467.

Abstract

Semiconductor (SC)-based field-effect transistors (FETs) have been demonstrated as amazing enhancer gadgets due to their delicate interface towards surface adsorption. This leads to their application as sensors and biosensors. Additionally, the semiconductor material has enormous recognizable fixation extends, high affectability, high consistency for solid detecting, and the ability to coordinate with other microfluidic gatherings. This review focused on current progress on the semiconductor-interfaced FET biosensor through the fundamental interface structure of sensor design, including inorganic semiconductor/aqueous interface, photoelectrochemical interface, nano-optical interface, and metal-assisted interface. The works that also point to a further advancement for the trademark properties mentioned have been reviewed here. The emergence of research on the organic semiconductor interface, integrated biosensors with Complementary metal-oxide-semiconductor (CMOS)-compatible, metal-organic frameworks, has accelerated the practical application of biosensors. Through a solid request for research along with sensor application, it will have the option to move forward the innovative sensor with the extraordinary semiconductor interface structure.

摘要

基于半导体(SC)的场效应晶体管(FET)因其对表面吸附的敏感界面而被证明是出色的增强型器件。这导致它们被用作传感器和生物传感器。此外,半导体材料具有巨大的可识别固定范围、高灵敏度、对固体检测的高一致性以及与其他微流控组件协调的能力。本综述重点介绍了通过传感器设计的基本界面结构,包括无机半导体/水界面、光电化学界面、纳米光学界面和金属辅助界面,在半导体界面 FET 生物传感器方面的最新进展。还审查了指向进一步提高所述商标性能的工作。有机半导体界面研究的出现以及与互补金属氧化物半导体(CMOS)兼容的集成生物传感器、金属有机骨架的出现,加速了生物传感器的实际应用。通过对传感器应用的坚实研究需求,它将能够通过出色的半导体界面结构推动创新传感器的发展。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8470/8156696/ad1c55ed31ee/sensors-21-03467-sch001.jpg

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