Homeier-Bachmann Timo, Heiden Stefan E, Lübcke Phillip K, Bachmann Lisa, Bohnert Jürgen A, Zimmermann Dirk, Schaufler Katharina
Friedrich-Loeffler-Institut, Institute of Epidemiology, 17493 Greifswald-Insel Riems, Germany.
Institute of Pharmacy, University of Greifswald, 17489 Greifswald, Germany.
Antibiotics (Basel). 2021 May 12;10(5):568. doi: 10.3390/antibiotics10050568.
Antibiotic-resistant are regularly detected in livestock. As pathogens, they cause difficult-to-treat infections and, as commensals, they may serve as a source of resistance genes for other bacteria. Slaughterhouses produce significant amounts of wastewater containing antimicrobial-resistant bacteria (AMRB), which are released into the environment. We analyzed the wastewater from seven slaughterhouses (pig and poultry) for extended-spectrum β-lactamase (ESBL)-carrying and colistin-resistant . AMRB were regularly detected in pig and poultry slaughterhouse wastewaters monitored here. All 25 ESBL-producing bacterial strains (19 and six ) isolated from poultry slaughterhouses were multidrug-resistant. In pig slaughterhouses 64% (12 of 21 [57%] and all four detected [100%]) were multidrug-resistant. Regarding colistin, resistant were detected in 54% of poultry and 21% of pig water samples. Carbapenem resistance was not detected. Resistant bacteria were found directly during discharge of wastewaters from abattoirs into water bodies highlighting the role of slaughterhouses for environmental surface water contamination.
抗生素耐药菌经常在牲畜中被检测到。作为病原体，它们会引发难以治疗的感染，而作为共生菌，它们可能成为其他细菌耐药基因的来源。屠宰场产生大量含有抗微生物耐药菌（AMRB）的废水，并排放到环境中。我们分析了7家屠宰场（猪和家禽屠宰场）废水中携带超广谱β-内酰胺酶（ESBL）和耐黏菌素的细菌。在此监测的猪和家禽屠宰场废水中经常检测到AMRB。从家禽屠宰场分离出的所有25株产ESBL细菌菌株（19株大肠杆菌和6株肺炎克雷伯菌）均具有多重耐药性。在猪屠宰场，64%（21株大肠杆菌中的12株[57%]和检测到的所有4株肺炎克雷伯菌[100%]）具有多重耐药性。关于黏菌素，在54%的家禽水样和21%的猪水样中检测到耐药菌。未检测到碳青霉烯类耐药菌。在屠宰场废水排入水体的过程中直接检测到耐药菌，突出了屠宰场对环境地表水的污染作用。
