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伪麻黄碱——益处与风险。

Pseudoephedrine-Benefits and Risks.

机构信息

Department of Clinical Pharmacology, Wroclaw Medical University, Borowska 211a St., 50-556 Wroclaw, Poland.

出版信息

Int J Mol Sci. 2021 May 13;22(10):5146. doi: 10.3390/ijms22105146.

Abstract

Pseudoephedrine (PSE) is a drug with a long history of medical use; it is helpful in treating symptoms of the common cold and flu, sinusitis, asthma, and bronchitis. Due to its central nervous system (CNS) stimulant properties and structural similarity to amphetamine, it is also used for non-medical purposes. The substance is taken as an appetite reducer, an agent which eliminates drowsiness and fatigue, to improve concentration and as a doping agent. Due to its easier availability, it is sometimes used as a substitute for amphetamine or methamphetamine. Pseudoephedrine is also a substrate (precursor) used in the production of these drugs. Time will tell whether legal restrictions on the sale of this drug will reduce the scale of the problem associated with its misuse.

摘要

伪麻黄碱(PSE)是一种具有悠久药用历史的药物;它有助于治疗普通感冒和流感、鼻窦炎、哮喘和支气管炎的症状。由于其对中枢神经系统(CNS)的刺激特性和与安非他命的结构相似性,它也被用于非医疗目的。这种物质被用作食欲抑制剂、消除嗜睡和疲劳的药物,以提高注意力并作为兴奋剂。由于其更容易获得,它有时被用作安非他命或甲基苯丙胺的替代品。伪麻黄碱也是生产这些药物的一种基质(前体)。时间将证明对这种药物销售的法律限制是否会减少与其滥用相关的问题的规模。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7140/8152226/46e8a24ae6bf/ijms-22-05146-g001.jpg

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