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溃疡性结肠炎合并低位直肠癌的管理：一种治疗算法的建议

Management of Low Rectal Cancer Complicating Ulcerative Colitis: Proposal of a Treatment Algorithm.

作者信息

Sensi Bruno, Bagaglini Giulia, Bellato Vittoria, Cerbo Daniele, Guida Andrea Martina, Khan Jim, Panis Yves, Savino Luca, Siragusa Leandro, Sica Giuseppe S

机构信息

Minimally Invasive Surgery, Department of Surgery, Policlinico Tor Vergata, 00133 Rome, Italy.

Colorectal Surgery Department, Queen Alexandra Hospital, Portsmouth NHS Trust, Portsmouth PO6 3LY, UK.

出版信息

Cancers (Basel). 2021 May 13;13(10):2350. doi: 10.3390/cancers13102350.

DOI:10.3390/cancers13102350
PMID:34068058
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8152518/
Abstract

Low rectal Carcinoma arising at the background of Ulcerative Colitis poses significant management challenges to the clinicians. The complex decision-making requires discussion at the multidisciplinary team meeting. The published literature is scarce, and there are significant variations in the management of such patients. We reviewed treatment protocols and operative strategies; with the aim of providing a practical framework for the management of low rectal cancer complicating UC. A practical treatment algorithm is proposed.

摘要

溃疡性结肠炎背景下发生的低位直肠癌给临床医生带来了重大的管理挑战。复杂的决策需要在多学科团队会议上进行讨论。已发表的文献很少，而且这类患者的管理存在很大差异。我们回顾了治疗方案和手术策略，旨在为溃疡性结肠炎并发低位直肠癌的管理提供一个实用框架。提出了一种实用的治疗算法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5bf0/8152518/a182d56c0f85/cancers-13-02350-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5bf0/8152518/d62c89f2829d/cancers-13-02350-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5bf0/8152518/536db5e5892c/cancers-13-02350-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5bf0/8152518/02f13680685c/cancers-13-02350-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5bf0/8152518/de5ad79e9ba4/cancers-13-02350-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5bf0/8152518/42f6f38012d0/cancers-13-02350-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5bf0/8152518/a182d56c0f85/cancers-13-02350-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5bf0/8152518/d62c89f2829d/cancers-13-02350-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5bf0/8152518/536db5e5892c/cancers-13-02350-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5bf0/8152518/02f13680685c/cancers-13-02350-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5bf0/8152518/de5ad79e9ba4/cancers-13-02350-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5bf0/8152518/42f6f38012d0/cancers-13-02350-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5bf0/8152518/a182d56c0f85/cancers-13-02350-g006.jpg

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Lancet Gastroenterol Hepatol. 2021 Feb;6(2):92-105. doi: 10.1016/S2468-1253(20)30333-2. Epub 2020 Dec 11.
2
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3
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BMC Gastroenterol. 2021 Oct 30;21(1):415. doi: 10.1186/s12876-021-01940-0.
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