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成功长期口服锌治疗显著型威尔逊病:一例报告

Successful long term oral zinc in florid Wilson's disease: a case report.

作者信息

Kaur U, Bambery P, Bhushnurmath S R, Deodhar S D, Dilawari J B

机构信息

Department of Experimental Medicine, Post Graduate Institute of Medical Education and Research, Chandigarh, India.

出版信息

Trop Geogr Med. 1988 Apr;40(2):161-5.

PMID:3407008
Abstract

We describe the clinical course of a patient with florid, predominantly neurological, Wilson's disease who developed serious toxic effects of d-penicillamine therapy but responded well to long term oral zinc sulphate. A congenital portosystemic shunt has decompressed the portal bed adequately to prevent the development of varices. We also documented the return to normal of a grossly abnormal pancreolauryl test after withdrawal of zinc.

摘要

我们描述了一位患有典型的、以神经症状为主的威尔逊氏病患者的临床病程,该患者在接受青霉胺治疗时出现了严重的毒性反应,但长期口服硫酸锌后反应良好。先天性门体分流已充分减压门静脉床,以防止静脉曲张的发生。我们还记录了停用锌后,严重异常的胰月桂基试验恢复正常的情况。

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[Treatment of Wilson's disease].[威尔逊氏病的治疗]
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