Flix-Díez Laura, Delicado-Miralles Miguel, Gurdiel-Álvarez Francisco, Velasco Enrique, Galán-Calle María, Lerma Lara Sergio
Department of Physical Therapy, University of Valencia (UV), 46003 Valencia, Spain.
Instituto de Neurociencias de Alicante (UMH-CSIC), 03550 Sant Joant d'Alacant, Spain.
Brain Sci. 2021 May 25;11(6):691. doi: 10.3390/brainsci11060691.
Transcranial direct current stimulation (tDCS) has been investigated as a way of improving motor learning. Our purpose was to explore the reversal bilateral tDCS effects on manual dexterity training, during five days, with the retention component measured after 5 days to determine whether somatosensory effects were produced. In this randomized, triple-blind clinical trial, 28 healthy subjects (14 women) were recruited and randomized into tDCS and placebo groups, although only 23 participants (13 women) finished the complete protocol. Participants received the real or placebo treatment during five consecutive days, while performing a motor dexterity training program of 20 min. The motor dexterity and the sensitivity of the hand were assessed pre- and post-day 1, post 5 days of training, and 5 days after training concluded. Training improved motor dexterity, but tDCS only produced a tendency to improve retention. The intervention did not produce changes in the somatosensory variables assessed. Thus, reversal bi-tDCS had no effects during motor learning on healthy subjects, but it could favor the retention of the motor skills acquired. These results do not support the cooperative inter-hemispheric model.
经颅直流电刺激（tDCS）已被作为一种改善运动学习的方法进行研究。我们的目的是探讨在为期五天的手动灵巧性训练中反向双侧tDCS的效果，并在五天后测量记忆成分，以确定是否产生了体感效应。在这项随机、三盲临床试验中，招募了28名健康受试者（14名女性）并随机分为tDCS组和安慰剂组，不过只有23名参与者（13名女性）完成了完整方案。参与者在连续五天接受真实或安慰剂治疗的同时，进行一项20分钟的运动灵巧性训练计划。在训练第1天前后、训练5天后以及训练结束5天后，对运动灵巧性和手部敏感性进行评估。训练改善了运动灵巧性，但tDCS仅产生了改善记忆的倾向。该干预并未使所评估的体感变量发生变化。因此，反向双侧tDCS在健康受试者的运动学习过程中没有效果，但可能有利于所获得运动技能的记忆。这些结果不支持半球间合作模型。
