da Silva Cunha de Medeiros Rafaela Catherine, Dos Santos Isis Kelly, de Oliveira Anna Luiza Vasconcelos, de Goes Carlos Jean Damasceno, de Medeiros Jason Azevedo, da Silva Tatiane Andreza Lima, de Souza Araujo Juliany, de Alcântara Varela Phelipe Wilde, Cobucci Ricardo Ney, de Araújo Tinoco Cabral Breno Guilherme, Dantas Paulo Moreira Silva
Graduate Program in Health Sciences, Federal University of Rio Grande do Norte, Natal 59078-970, Brazil.
Department of Nutrition, Federal University of Rio Grande do Norte, Natal 59078-970, Brazil.
Int J Environ Res Public Health. 2021 May 26;18(11):5675. doi: 10.3390/ijerph18115675.
: The adverse effects of antiretroviral therapy associated with complications generated by human immunodeficiency virus (HIV) promote impairments in physical fitness in adolescents. : To analyze the aerobic capacity, muscle strength, and body composition of adolescents living with HIV compared with a healthy population of the same age. : Searches were performed in the MEDLINE, Embase, Web of Science, Scopus and SportDiscus databases until September 2019 and updated in April 2020. Eligibility Criteria: adolescents of both sexes in the age group from 10 to 19 years; living with HIV; cross-sectional, case-control, cohort studies; comparing with a healthy population. Mean differences and 95% Confidence intervals (CIs) were calculated using RevMan (software for systematic reviews). : Five articles were included, involving 197 adolescents living with HIV (16 to 18 years) and 185 without infection (13 to 18 years), with the sample in each study ranging from 15 to 65 adolescents. Aerobic capacity and muscle strength were reduced in adolescents with HIV, and body mass index was also significantly lower in this group. : Adolescents living with HIV have impaired cardiorespiratory fitness, muscle strength, and body composition when compared to their uninfected peers. However, this systematic review provides limited evidence on the differences between the physical fitness outcomes of adolescents living with HIV compared to healthy adolescents.
抗逆转录病毒疗法的不良反应与人类免疫缺陷病毒（HIV）引发的并发症相关，会导致青少年身体健康受损。
分析感染HIV的青少年与同龄健康人群相比的有氧能力、肌肉力量和身体成分。
截至2019年9月在MEDLINE、Embase、科学网、Scopus和SportDiscus数据库中进行检索，并于2020年4月更新。纳入标准：年龄在10至19岁的青少年；感染HIV；横断面研究、病例对照研究、队列研究；与健康人群进行比较。使用RevMan（系统评价软件）计算平均差异和95%置信区间（CI）。
纳入五篇文章，涉及197名感染HIV的青少年（16至18岁）和185名未感染的青少年（13至18岁），每项研究的样本量为15至65名青少年。感染HIV的青少年有氧能力和肌肉力量下降，且该组的体重指数也显著较低。
与未感染的同龄人相比，感染HIV的青少年心肺功能、肌肉力量和身体成分受损。然而，这项系统评价提供的关于感染HIV的青少年与健康青少年身体素质结果差异的证据有限。
