Rajendraprasad Sanu, Destache Christopher, Quimby David
School of Medicine, Creighton University, Omaha, NE 68124, USA.
College of Pharmacy, Creighton University, Omaha, NE 68124, USA.
Infect Dis Rep. 2021 May 24;13(2):454-464. doi: 10.3390/idr13020045.
Nontuberculous mycobacterial (NTM) genitourinary (GU) infections are relatively rare, and there is frequently a delay in diagnosis. Mycobacterium avium-intracellulare complex (MAC) cases seem to be less frequent than other NTM as a cause of these infections. In addition, there are no set treatment guidelines for these organisms in the GU tract. Given the limitations of data this review summarizes a case presentation of this infection and the literature available on the topic. Many different antimicrobial regimens and durations have been used in the published literature. While the infrequency of these infections suggests that there will not be randomized controlled trials to determine optimal therapy, our case suggests that a brief course of amikacin may play a useful role in those who cannot tolerate other antibiotics.
非结核分枝杆菌（NTM）引起的泌尿生殖系统（GU）感染相对罕见，且诊断常常延迟。鸟分枝杆菌胞内菌复合体（MAC）作为这些感染的病因，似乎比其他NTM少见。此外，对于泌尿生殖道中的这些病原体，尚无既定的治疗指南。鉴于数据的局限性，本综述总结了该感染的病例报告以及该主题的现有文献。已发表的文献中使用了许多不同的抗菌方案和疗程。虽然这些感染的罕见性表明不会有随机对照试验来确定最佳治疗方法，但我们的病例表明，对于无法耐受其他抗生素的患者，短期使用阿米卡星可能会发挥有益作用。
