Department of Community Health Sciences, Clinical Nutrition Program, College of Applied Medical Sciences, King Saud University, Riyadh, Saudi Arabia.
Sci Rep. 2021 Jun 1;11(1):11522. doi: 10.1038/s41598-021-91108-3.
Vitamin D deficiency prevalence in children has been rising. Low 25-hydroxyvitamin D3 (25(OH)D3) levels contribute to poor asthma control in children. This study assessed 25(OH)D3 levels in children with asthma from Riyadh with respect to anthropometrics, dietary, and lifestyle variables. Children with asthma (n, 60; 2-17 years) were assessed for serum 25-hydroxy vitamin D3 (25(OH)D3) level and body anthropometrics (weight, height, and body mass index [BMI]). Vitamin D dietary intake, sun exposure, and sociodemographic data were collected using a structured questionnaire. Thirty-one children (52%) had a 25(OH)D3 level < 50 nmol/L, 15 of whom (25%) had a level < 30 nmol/L. 25(OH)D3 level was significantly negatively correlated with age (P < 0.05), weight (P < 0.02), and height (P < 0.05). Children with a 25(OH)D3 level < 30 nmol/L had a significantly higher BMI than children with insufficient and sufficient vitamin D levels (P < 0.01). There was no significant effect of sex on 25(OH)D3 level. Higher 25(OH)D3 level was associated with a greater body area exposure to the sun. This study found that > 50% of the children with asthma had below sufficiency vitamin D levels. The vitamin D screening and supplementation of older and overweight children with asthma is recommended.
儿童维生素 D 缺乏症的患病率一直在上升。低水平的 25-羟维生素 D3（25(OH)D3）会导致儿童哮喘控制不佳。本研究评估了利雅得哮喘儿童的 25(OH)D3 水平与人体测量学、饮食和生活方式变量的关系。评估了 60 名哮喘儿童（2-17 岁）的血清 25-羟维生素 D3（25(OH)D3）水平和人体测量学（体重、身高和体重指数 [BMI]）。使用结构化问卷收集维生素 D 饮食摄入、阳光暴露和社会人口统计学数据。31 名儿童（52%）的 25(OH)D3 水平<50nmol/L，其中 15 名儿童（25%）的水平<30nmol/L。25(OH)D3 水平与年龄呈显著负相关（P<0.05）、体重（P<0.02）和身高（P<0.05）。25(OH)D3 水平<30nmol/L 的儿童 BMI 明显高于维生素 D 水平不足和充足的儿童（P<0.01）。性别对 25(OH)D3 水平无显著影响。25(OH)D3 水平较高与更大的身体面积暴露于阳光下有关。本研究发现，超过 50%的哮喘儿童维生素 D 水平不足。建议对年龄较大和超重的哮喘儿童进行维生素 D 筛查和补充。
