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成人脑瘫患者的睡眠呼吸紊乱:目前我们了解多少?

Sleep Disordered Breathing in Adults with Cerebral Palsy: What Do We Know So Far?

机构信息

From the Division of General Internal Medicine, University of Florida College of Medicine, Jacksonville.

出版信息

South Med J. 2021 Jun;114(6):339-342. doi: 10.14423/SMJ.0000000000001264.

DOI:10.14423/SMJ.0000000000001264
PMID:34075423
Abstract

As advances in medicine continue to extend the lifespan of patients with cerebral palsy (CP), emphasis must be placed on evaluating patients for chronic health issues common in the general adult population. Sleep-disordered breathing (SDB) affects a large number of otherwise healthy adults and is even more common in individuals with disability. SDB includes the following subtypes: obstructive sleep apnea, central sleep apnea, and sleep-related hypoventilation/hypoxemia. SDB consequences include poor daytime functioning from sleepiness and an increased risk of cardiovascular morbidity and mortality. There is a paucity of data available in the literature about the association between SDB and CP in the adult population. More research is needed to understand the true prevalence and management strategies of SDB in patients with CP. This review focuses on three major subtypes of SDB: obstructive sleep apnea, central sleep apnea, and sleep-related hypoventilation/hypoxemia.

摘要

随着医学的进步不断延长脑瘫(CP)患者的寿命,必须重视评估患者是否存在一般成年人群中常见的慢性健康问题。睡眠呼吸障碍(SDB)影响大量其他健康成年人,在残疾人群中更为常见。SDB 包括以下亚型:阻塞性睡眠呼吸暂停、中枢性睡眠呼吸暂停和与睡眠相关的通气不足/低氧血症。SDB 的后果包括嗜睡导致白天功能不佳,以及心血管发病率和死亡率增加。关于成人 SDB 和 CP 之间的关联,文献中提供的数据很少。需要更多的研究来了解 CP 患者 SDB 的真实患病率和管理策略。本综述重点介绍 SDB 的三个主要亚型:阻塞性睡眠呼吸暂停、中枢性睡眠呼吸暂停和与睡眠相关的通气不足/低氧血症。

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