Nippon Soda Co. Ltd., Chiba Research Center, 12-54 Goi-minamikaigan, Ichihara, Chiba 290-0045, Japan.
College of Science, Department of Chemistry, Rikkyo University, 3-34-1 Nishi-Ikebukuro, Toshima-ku, Tokyo, 171-8501, Japan.
Dalton Trans. 2021 Jun 1;50(21):7176-7180. doi: 10.1039/d1dt00733e.
Novel metal-organic frameworks (MOFs) based on thiabendazole (TBZ) were developed. The two structurally distinct TBZ-MOFs synthesized in this study exhibited enhanced durability and a broader biocidal spectrum than either individual bioactive species (i.e., Zn2+ and TBZ). The characteristics of each TBZ-MOF are related to the coordination modes among the Zn2+ ions and ligand donors. The difference in water solubility between the two TBZ-MOFs due to the structural design allows for the controlled release of the desired bioactive component.
本研究合成了两种结构独特的噻菌灵（TBZ）基金属-有机骨架（MOFs），它们的耐用性和杀菌谱均优于单一活性物质（即 Zn2+和 TBZ）。两种 TBZ-MOF 的特性与 Zn2+离子和配体供体之间的配位模式有关。两种 TBZ-MOF 因结构设计而导致的水溶性差异可实现所需活性成分的控制释放。
