Department of Public Health and Policy, University of Liverpool, Liverpool, UK.
Liverpool Reviews and Implementation Group, University of Liverpool, Liverpool, UK.
Health Technol Assess. 2021 May;25(35):1-234. doi: 10.3310/hta25350.
Local authorities in England commission the NHS Health Check programme to invite everyone aged 40-74 years without pre-existing conditions for risk assessment and eventual intervention, if needed. However, the programme's effectiveness, cost-effectiveness and equity impact remain uncertain.
To develop a validated open-access flexible web-based model that enables local commissioners to quantify the cost-effectiveness and potential for equitable population health gain of the NHS Health Check programme.
The objectives were as follows: (1) co-produce with stakeholders the desirable features of the user-friendly model; (2) update the evidence base to support model and scenario development; (3) further develop our computational model to allow for developments and changes to the NHS Health Check programme and the diseases it addresses; (4) assess the effectiveness, cost-effectiveness and equity of alternative strategies for implementation to illustrate the use of the tool; and (5) propose a sustainability and implementation plan to deploy our user-friendly computational model at the local level.
Co-production workshops surveying the best-performing local authorities and a systematic literature review of strategies to increase uptake of screening programmes informed model use and development. We then co-produced the workHORSE (working Health Outcomes Research Simulation Environment) model to estimate the health, economic and equity impact of different NHS Health Check programme implementations, using illustrative-use cases.
Local authorities in England.
Stakeholders from local authorities, Public Health England, the NHS, the British Heart Foundation, academia and other organisations participated in the workshops. For the local authorities survey, we invited 16 of the best-performing local authorities in England.
The user interface allows users to vary key parameters that represent programme activities (i.e. invitation, uptake, prescriptions and referrals). Scenarios can be compared with each other.
Disease cases and case-years prevented or postponed, incremental cost-effectiveness ratios, net monetary benefit and change in slope index of inequality.
The survey of best-performing local authorities revealed a diversity of effective approaches to maximise the coverage and uptake of NHS Health Check programme, with no distinct 'best buy'. The umbrella literature review identified a range of effective single interventions. However, these generally need to be combined to maximally improve uptake and health gains. A validated dynamic, stochastic microsimulation model, built on robust epidemiology, enabled service options analysis. Analyses of three contrasting illustrative cases estimated the health, economic and equity impact of optimising the Health Checks, and the added value of obtaining detailed local data. Optimising the programme in Liverpool can become cost-effective and equitable, but simply changing the invitation method will require other programme changes to improve its performance. Detailed data inputs can benefit local analysis.
Although the approach is extremely flexible, it is complex and requires substantial amounts of data, alongside expertise to both maintain and run.
Our project showed that the workHORSE model could be used to estimate the health, economic and equity impact comprehensively at local authority level. It has the potential for further development as a commissioning tool and to stimulate broader discussions on the role of these tools in real-world decision-making.
Future work should focus on improving user interactions with the model, modelling simulation standards, and adapting workHORSE for evaluation, design and implementation support.
This study is registered as PROSPERO CRD42019132087.
This project was funded by the National Institute for Health Research (NIHR) Health Technology Assessment programme and will be published in full in ; Vol. 25, No. 35. See the NIHR Journals Library website for further project information.
英格兰地方当局委托国民保健制度健康检查计划邀请所有 40-74 岁没有预先存在的疾病风险评估和必要干预的人。然而,该计划的效果、成本效益和公平性影响仍不确定。
开发一个经过验证的、可公开获取的灵活的网络模型,使地方委员会能够量化国民保健制度健康检查计划的成本效益和公平获得人口健康的潜力。
(1)与利益相关者共同制定用户友好型模型的理想功能;(2)更新证据基础,以支持模型和情景开发;(3)进一步开发我们的计算模型,以适应国民保健制度健康检查计划及其解决的疾病的发展和变化;(4)评估替代实施策略的效果、成本效益和公平性,以说明工具的使用;(5)提出可持续性和实施计划,以在地方层面部署我们的用户友好型计算模型。
合作制作研讨会调查表现最佳的地方当局和系统的文献综述,以增加筛选计划的参与率,为模型使用和开发提供信息。然后,我们共同开发了 workHORSE(工作健康结果研究模拟环境)模型,以使用说明性使用案例来估计不同国民保健制度健康检查计划实施的健康、经济和公平影响。
英格兰地方当局。
来自地方当局、英国公共卫生署、国民保健制度、英国心脏基金会、学术界和其他组织的利益相关者参加了研讨会。对于地方当局调查,我们邀请了英格兰表现最好的 16 个地方当局。
用户界面允许用户改变代表计划活动的关键参数(即邀请、参与、处方和转诊)。可以对方案进行比较。
疾病病例和预防或推迟的病例年数、增量成本效益比、净货币收益和不平等斜率指数的变化。
对表现最佳的地方当局的调查揭示了各种有效的方法来最大限度地提高国民保健制度健康检查计划的覆盖面和参与率,没有明显的“最佳购买”。伞式文献综述确定了一系列有效的单一干预措施。然而,这些措施通常需要结合使用,以最大限度地提高参与度和健康收益。一个经过验证的动态、随机的微观模拟模型,建立在稳健的流行病学基础上,使服务选项分析成为可能。对三个对比案例的分析估计了优化健康检查的健康、经济和公平影响,以及获得详细的地方数据的附加值。在利物浦优化该计划可以变得具有成本效益和公平性,但仅仅改变邀请方法将需要其他计划变更来提高其绩效。详细的数据输入可以使地方分析受益。
尽管该方法非常灵活,但它很复杂,需要大量的数据和专业知识来维护和运行。
我们的项目表明,workHORSE 模型可以在地方当局层面上全面估计健康、经济和公平影响。它具有进一步发展为一种委托工具的潜力,并能激发更广泛地讨论这些工具在实际决策中的作用。
未来的工作应侧重于改进模型与用户的交互,模拟标准的建模以及为评估、设计和实施支持而调整 workHORSE。
本研究已在 PROSPERO CRD42019132087 中注册。
本项目由英国国家卫生研究院(NIHR)健康技术评估计划资助,将在 ; Vol. 25, No. 35 中全文发表。有关该项目的更多信息,请访问 NIHR 期刊库网站。