Balla Mamtha, Merugu Ganesh, Nesheiwat Zeid, Patel Mitra, Sheikh Taha, Fatima Rawish, Kotturi Vinay K, Bommana Venugopal, Pulagam Gautham, Kaminski Brian
Internal Medicine, ProMedica Toledo Hospital, Toledo, USA.
Internal Medicine, The University of Toledo Medical Center, Toledo, USA.
Cureus. 2021 Apr 5;13(4):e14308. doi: 10.7759/cureus.14308.
Background There is limited data on the clinical characteristics and predictors of mortality of coronavirus disease-2019 (COVID-19) in North West Ohio. We performed a retrospective review of patients hospitalized with COVID-19 in the ProMedica Health System in Northwest Ohio from March 25 to June 16, 2020. The study aims to identify epidemiological, clinical characteristics, and predictors of Mortality of COVID-19 patients in Northwest Ohio. Methods This study was conducted on 217 COVID-19 patients admitted to ProMedica Health System Hospitals in Northwest Ohio from March 25 to June 16, 2020. We collected data, including clinical signs, symptoms, and outcomes of the COVID-19 patients. We compared clinical signs and symptoms along with comorbidities of survivors and non-survivors. Results Of the 217 patients included in the study, the mean age of the population was 63.13 (SD 17.8), of which 194 (89.4%, mean age 61.7 years) survived while 23 (10.6%, mean age 74.6 years) died. Among them, 53% were females and 47% male. Common presenting symptoms were chest pain (91.71%), shortness of breath (79.7%), cough (71%), and fever (64%). Mortality was associated with age greater than 63 (p-value 0.0052) and hypertension (p-value: 0.0058) with marginal significance with gender (p-value: 0.0642), chest pain (p-value: 0.0944), and history of cancer (p-value: 0.0944). Conclusions Advanced age and hypertension (HTN) are independent predictors for increased mortality. History of cancer and chest pain are associated with increased mortality with marginal significance. Awareness among physicians about predictors of mortality is essential in dealing with COVID-19 patients. It is essential to educate the public about preventative strategies such as wearing masks to decrease mortality and morbidity from this pandemic.
关于俄亥俄州西北部2019冠状病毒病（COVID-19）的临床特征和死亡率预测因素的数据有限。我们对2020年3月25日至6月16日在俄亥俄州西北部普罗梅迪卡医疗系统住院的COVID-19患者进行了回顾性研究。该研究旨在确定俄亥俄州西北部COVID-19患者的流行病学、临床特征和死亡率预测因素。方法：本研究对2020年3月25日至6月16日入住俄亥俄州西北部普罗梅迪卡医疗系统医院的217例COVID-19患者进行。我们收集了数据，包括COVID-19患者的临床体征、症状和结局。我们比较了幸存者和非幸存者的临床体征、症状以及合并症。结果：在纳入研究的217例患者中，人群平均年龄为63.13岁（标准差17.8），其中194例（89.4%，平均年龄61.7岁）存活，23例（10.6%，平均年龄74.6岁）死亡。其中，53%为女性，47%为男性。常见的症状有胸痛（91.71%）、呼吸急促（79.7%）、咳嗽（71%）和发热（64%）。死亡率与年龄大于63岁（p值0.0052）和高血压（p值：0.0058）相关，与性别（p值：0.0642）、胸痛（p值：0.0944）和癌症病史（p值：0.0944）有边际显著性关联。结论：高龄和高血压（HTN）是死亡率增加的独立预测因素。癌症病史和胸痛与死亡率增加有边际显著性关联。医生了解死亡率预测因素对于治疗COVID-19患者至关重要。对公众进行预防策略教育，如佩戴口罩，以降低这一流行病的死亡率和发病率至关重要。
