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硬膜外脓肿:一种不容错过的背痛病因。

Epidural Abscess: A Cause of Back Pain That Must Not Be Missed.

作者信息

Egídio de Sousa Inês, Brito Monteiro Margarida, Piteira Maria, Cuco António, Telles Freitas Paulo

机构信息

Internal Medicine Department, Hospital São Francisco Xavier, Lisbon, PRT.

Internal Medicine Department, Hospital Prof. Doutor Fernando Fonseca, Amadora, PRT.

出版信息

Cureus. 2021 Apr 9;13(4):e14376. doi: 10.7759/cureus.14376.

DOI:10.7759/cureus.14376
PMID:34079646
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8159304/
Abstract

Low back and cervical pain are common emergency department complaints. Most cases represent low-risk pathologies but in rare cases, it can be a symptom of a serious underlying disease and the distinction can be challenging. A case is reported of a 58-year-old male with recurrent cervical pain requiring several emergency department visits. He eventually presented with intense cervical and low back pain, tetraparesis, and dyspnea. His condition deteriorated in less than 24 hours, evolving with fever, shock, and respiratory insufficiency and was admitted to the Intensive Care Unit for aminergic support, invasive mechanical ventilation and started on empiric antibiotics. Investigations revealed raised inflammatory markers and a cervical pre-vertebral purulent collection associated with an epidural collection at the level of C2 to C5 with spinal cord compression. The patient underwent transoral drainage and removal of the posterior C1 arch along with C2-C3-C4-C5 laminectomy. Staphylococcus aureus was isolated in the blood, pus, and bone. Re-intervention was required due to persistent pre-vertebral abscesses with clinical improvement thereafter. Eight weeks of antibiotic treatment were completed in total. The patient was discharged after 72 days of hospitalization with significant improvement in force and autonomy. Epidural abscess is a rare finding that can cause rapid irreversible neurological deterioration. Clinical suspicion must be high for an early diagnosis and treatment, essential for a better prognosis.

摘要

腰背痛和颈痛是急诊科常见的主诉。大多数病例为低风险病变,但在极少数情况下,它可能是严重潜在疾病的症状,而鉴别诊断可能具有挑战性。本文报告一例58岁男性,反复出现颈痛,多次到急诊科就诊。他最终出现剧烈的颈痛和腰背痛、四肢轻瘫及呼吸困难。其病情在不到24小时内恶化,伴有发热、休克和呼吸功能不全,被收入重症监护病房接受胺能支持、有创机械通气,并开始经验性使用抗生素。检查发现炎症指标升高,颈前有脓性积液,伴有C2至C5水平的硬膜外积液及脊髓受压。患者接受了经口引流、C1后弓切除及C2 - C3 - C4 - C5椎板切除术。血液、脓液和骨中分离出金黄色葡萄球菌。因持续存在颈前脓肿需再次干预,此后临床症状改善。总共完成了8周的抗生素治疗。患者住院72天后出院,肌力和自主能力有显著改善。硬膜外脓肿是一种罕见的疾病,可导致快速不可逆的神经功能恶化。临床必须高度怀疑以早期诊断和治疗,这对改善预后至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8939/8159304/e05a71325365/cureus-0013-00000014376-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8939/8159304/a10ab6bc1fdc/cureus-0013-00000014376-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8939/8159304/e05a71325365/cureus-0013-00000014376-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8939/8159304/a10ab6bc1fdc/cureus-0013-00000014376-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8939/8159304/e05a71325365/cureus-0013-00000014376-i02.jpg

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本文引用的文献

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When Is Imaging Appropriate for a Patient With Low Back Pain?对于腰痛患者,何时进行影像学检查合适?
Ochsner J. 2020 Fall;20(3):248-249. doi: 10.31486/toj.20.0077.
2
Spinal Epidural Abscess: A Review of Presentation, Management, and Medicolegal Implications.脊柱硬膜外脓肿:临床表现、治疗及法医学意义综述
Asian Spine J. 2020 Oct;14(5):742-759. doi: 10.31616/asj.2019.0369. Epub 2020 Jul 29.
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Management of cervical spine epidural abscess: a systematic review.颈椎硬膜外脓肿的管理:一项系统评价
Ther Adv Infect Dis. 2019 Jul 19;6:2049936119863940. doi: 10.1177/2049936119863940. eCollection 2019 Jan-Dec.
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Spinal Epidural Abscess: A Series of 101 Cases.脊柱硬膜外脓肿:101例病例系列
Am J Med. 2017 Dec;130(12):1458-1463. doi: 10.1016/j.amjmed.2017.07.017. Epub 2017 Aug 7.
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Prevalence of low back pain in emergency settings: a systematic review and meta-analysis.急诊环境下腰痛的患病率:一项系统评价与荟萃分析。
BMC Musculoskelet Disord. 2017 Apr 4;18(1):143. doi: 10.1186/s12891-017-1511-7.
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Upper Cervical Epidural Abscess in Clinical Practice: Diagnosis and Management.临床实践中的上颈椎硬膜外脓肿:诊断与处理。
Global Spine J. 2016 Jun;6(4):383-93. doi: 10.1055/s-0035-1565260. Epub 2015 Oct 13.