Zhang Nan, Xiong Wei, Li Yu, Mao Qinxiang, Xu Shangdong, Zhu Junming, Sun Zhonghua, Sun Lizhong
Department of Radiology, Beijing Anzhen Hospital, Capital Medical University, Beijing, China.
Department of Respiration, First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin, China.
Quant Imaging Med Surg. 2021 Jun;11(6):2861-2878. doi: 10.21037/qims-20-941.
Infectious aortitis (IA) is a rare and life-threatening cardiovascular disease. Early diagnosis and timely intervention are crucial for reducing mortality associated with mycotic aortic aneurysms (MAAs); however, early diagnosis is challenging due to the nonspecific symptoms. Some cases are diagnosed at an advanced stage or after developing complications, such as rupture or aortic fistula. Current state-of-the-art imaging modalities-including computed tomography (CT), magnetic resonance imaging (MRI), and 18F-fluorodeoxyglucose (FDG) positron emission tomography (PET)/CT-can detect infected aneurysms in clinically suspicious cases. MAA features on imaging include lobulated pseudoaneurysm, indistinct irregular arterial wall, perianeurysmal gas, perianeurysmal edema, perianeurysmal soft tissue mass, aneurysmal thrombosis, and high metabolic activity with increased uptake of FDG. Enlarged lymph nodes are often found adjacent to the aneurysm, while iliopsoas abscess (IPA), spondylitis, and aortic fistulas are commonly associated complications. After surgery or endovascular repair, radiological features-including ectopic gas, peri-graft fluid, thickening of adjacent bowel, pseudoaneurysm formed at the graft anastomosis, and increased uptake of FDG-may indicate an infection of aortic graft. This article provides an overview of the clinical and imaging features of MAAs. Thus, familiarity with the imaging appearances of MAAs may assist radiologists in the diagnosis and facilitation of timely treatment.
感染性主动脉炎(IA)是一种罕见且危及生命的心血管疾病。早期诊断和及时干预对于降低与真菌性主动脉瘤(MAA)相关的死亡率至关重要;然而,由于症状不具特异性,早期诊断具有挑战性。一些病例在晚期或出现诸如破裂或主动脉瘘等并发症后才得以诊断。当前的先进成像方式,包括计算机断层扫描(CT)、磁共振成像(MRI)以及18F-氟脱氧葡萄糖(FDG)正电子发射断层扫描(PET)/CT,能够在临床可疑病例中检测出感染性动脉瘤。MAA的影像学特征包括分叶状假性动脉瘤、动脉壁模糊不清、动脉瘤周围气体、动脉瘤周围水肿、动脉瘤周围软组织肿块、动脉瘤内血栓形成以及FDG摄取增加导致的高代谢活性。动脉瘤附近常可发现肿大淋巴结,而髂腰肌脓肿(IPA)、脊柱炎和主动脉瘘是常见的相关并发症。手术或血管腔内修复后,包括异位气体、移植物周围液体、相邻肠管增厚、移植物吻合处形成假性动脉瘤以及FDG摄取增加等影像学特征,可能提示主动脉移植物感染。本文概述了MAA的临床和影像学特征。因此,熟悉MAA的影像学表现可能有助于放射科医生进行诊断并促进及时治疗。