Molecular Sensors and Therapeutics Research Laboratory, Department of Chemistry, School of Natural Sciences, Shiv Nadar University, NH 91, Tehsil Dadri, Gautam Buddha Nagar, Uttar Pradesh 201314, India.
Chem Commun (Camb). 2021 Jun 29;57(52):6380-6383. doi: 10.1039/d1cc02600c.
A unique and highly water-soluble ICT-based fluorescent probe is developed for efficient detection and discrimination of reactive monocarbonyl formaldehyde (FA) from dicarbonyl methylglyoxal (MGO)/glyoxal (GO) by modulating the ICT process, which was confirmed by photophysical and TD-DFT analysis. The probe is applied in cellular imaging and quantifying FA in preserved food and MGO in manuka honey.
开发了一种独特的、高水溶性的 ICT 基荧光探针，通过调节 ICT 过程，可有效检测和区分反应性单羰基甲缩醛（FA）与二羰基甲基乙二醛（MGO）/乙二醛（GO），这一点通过光物理和 TD-DFT 分析得到了证实。该探针可用于细胞成像，并定量测定保藏食品中的 FA 和麦卢卡蜂蜜中的 MGO。
