Department of Food Science, Centre of Innovative Food Research (iFood), Aarhus University, Agro Food Park 48, 8200 Aarhus N, Denmark.
European Commission, Joint Research Centre (JRC), Geel, Belgium.
Food Chem. 2021 Nov 1;361:129998. doi: 10.1016/j.foodchem.2021.129998. Epub 2021 May 1.
A simple and fast method was developed for the simultaneous determination of 75 plastic food contact material (FCM) in liquid food simulants, at levels of a few ng g. The method employs an optimised salt-assisted liquid-liquid extraction for all EU-regulated ethanol/HO food simulants, in the presence of 10% NaCl (simulants A and C) or 5% NaCl (simulant D1), and dichloromethane as the extracting solvent. Gas chromatography with triple-quad MS operating in multiple reaction monitoring acquisition was used, applying isotope dilution with selected deuterated compounds. Adequate sensitivity was demonstrated for all analytes. The results also showed sufficient accuracy for the majority of substances, with recoveries of 70-120% and repeatability (expressed as relative standard deviations, RSDs) smaller than 15%. The method was applied to the analysis of FCM multilayer items after undergoing migration testing according to the specifications of the current EU legislation in force.
建立了一种简单快速的方法，用于在数 ng g 水平下同时测定液体食品模拟物中 75 种塑料食品接触材料（FCM）。该方法采用优化的盐辅助液液萃取，适用于所有欧盟规定的乙醇/高水食品模拟物，在存在 10% NaCl（模拟物 A 和 C）或 5% NaCl（模拟物 D1）的情况下，以及二氯甲烷作为萃取溶剂。采用三重四极杆 MS 进行气相色谱分析，采用选定的氘代化合物进行同位素稀释。所有分析物均表现出足够的灵敏度。结果还表明，对于大多数物质，回收率为 70-120%，重复性（表示为相对标准偏差，RSD）小于 15%，具有足够的准确性。该方法应用于根据现行欧盟法规的规定进行迁移测试后 FCM 多层物品的分析。
