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IBS 的低 FODMAP 饮食;一项评估长期随访的英国多中心研究。

The low FODMAP diet for IBS; A multicentre UK study assessing long term follow up.

机构信息

Academic Unit of Gastroenterology, Royal Hallamshire Hospital, Sheffield Teaching Hospital NHS Foundation Trust, Sheffield S10 2JF, United Kingdom; Academic Unit of Gastroenterology, Department of Infection, Immunity and Cardiovascular Disease, University of Sheffield, Sheffield, United Kingdom.

Academic Unit of Gastroenterology, Royal Hallamshire Hospital, Sheffield Teaching Hospital NHS Foundation Trust, Sheffield S10 2JF, United Kingdom.

出版信息

Dig Liver Dis. 2021 Nov;53(11):1404-1411. doi: 10.1016/j.dld.2021.05.004. Epub 2021 Jun 1.

Abstract

BACKGROUND

The low FODMAP diet (LFD) is effective in managing irritable bowel syndrome (IBS) in the short term. This study assessed the long-term effect of the LFD on symptoms, nutritional composition and socialising.

METHODS

Patients with IBS who received dietetic-led LFD advice were approached at long term follow up (>6 months post LFD advice) from six centres across the United Kingdom. Participants completed questionnaires assessing gastrointestinal symptoms, adherence, nutritional intake, dietary acceptability and food related quality of life (QOL).

RESULTS

205 participants completed the study, with a mean follow up of 44 months (3.7 years). Adequate symptom relief was noted in 60% of individuals at long term follow up, with 76% being on the personalisation phase of the LFD (pLFD). Mean nutritional intake did not differ between individuals on the pLFD versus habitual diet, with no difference in fructan intake (2.9 g/d vs 2.9 g/d, p = 0.96). The majority (80%) of individuals on the pLFD consumed specific 'free-from' products at the long term, with the purchase of gluten or wheat free products being the commonest (68%).

CONCLUSION

The majority of patients follow the pLFD in the long term, with a large proportion purchasing gluten or wheat free products to manage their symptoms.

摘要

背景

低 FODMAP 饮食(LFD)在短期内对肠易激综合征(IBS)有效。本研究评估了 LFD 对症状、营养成分和社交的长期影响。

方法

在英国六个中心,从接受饮食指导 LFD 建议的 IBS 患者中,在长期随访(LFD 建议后>6 个月)时进行研究。参与者完成了评估胃肠道症状、依从性、营养摄入、饮食可接受性和与食物相关的生活质量(QOL)的问卷。

结果

205 名参与者完成了研究,平均随访时间为 44 个月(3.7 年)。在长期随访中,60%的人有足够的症状缓解,76%的人处于 LFD 的个性化阶段(pLFD)。pLFD 与习惯性饮食相比,个体的平均营养摄入没有差异,果糖摄入量也没有差异(2.9g/d 与 2.9g/d,p=0.96)。大多数(80%)pLFD 个体在长期服用特定的“无”产品,最常见的是购买无麸质或无小麦产品(68%)。

结论

大多数患者在长期内遵循 pLFD,其中很大一部分人购买无麸质或无小麦产品来控制症状。

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