Prasad Harikrishnan, Kumar Gopal Shiva, Rajmohan Muthusamy, Varkey Korath
Department of Oral Pathology and Microbiology, KSR Institute of Dental Science and Research, Tiruchengode, Tamil Nadu, India.
Dr Paulose Dental Clinic and Maxillofacial Centre, Salem, Tamil Nadu, India.
J Oral Maxillofac Pathol. 2021 Mar;25(Suppl 1):S84-S89. doi: 10.4103/jomfp.JOMFP_249_20. Epub 2021 Mar 19.
The World Health Organization (WHO) classification of odontogenic tumors, in its different iterations, has seen several modifications in benign mixed odontogenic tumors. Odontoma is a benign mixed odontogenic tumor that shows dental hard tissue formation to varying degrees. Although odontomas are the most common odontogenic tumors, they are mostly seen in the form of compound odontomas, where the dental hard tissues resemble tooth-like structures. Complex odontoma shows a haphazard mass of dental hard tissues and is generally identified at an older age (mean age of around 20 years). Incidence of complex odontoma in very young children is quite rare, with only around 10 cases associated with the primary dentition being reported in the literature till date. Unlike other odontomas, our case showed an active epithelial component in the form of tooth buds and ameloblastic follicles along with the hard tissues, which made it difficult to distinguish from other similar lesions like ameloblastic fibroma with hard tissue formation and ameloblastoma arising from an odontoma. This article reports the 11th case of complex odontoma associated with the primary dentition, and the youngest such case to be reported in the Indian population.
世界卫生组织(WHO)对牙源性肿瘤的分类在其不同版本中,对良性混合性牙源性肿瘤进行了多次修改。成釉细胞瘤是一种良性混合性牙源性肿瘤,不同程度地表现出牙硬组织形成。尽管成釉细胞瘤是最常见的牙源性肿瘤,但它们大多以复合性成釉细胞瘤的形式出现,其中牙硬组织类似牙齿样结构。复杂性成釉细胞瘤表现为牙硬组织的杂乱团块,通常在年龄较大时(平均年龄约20岁)被发现。在非常年幼的儿童中,复杂性成釉细胞瘤的发病率相当罕见,迄今为止,文献中仅报道了约10例与乳牙列相关的病例。与其他成釉细胞瘤不同,我们的病例显示出活跃的上皮成分,表现为牙蕾和成釉细胞滤泡以及硬组织,这使得它难以与其他类似病变区分开来,如伴有硬组织形成的成釉细胞纤维瘤和由成釉细胞瘤发生的成釉细胞瘤。本文报道了第11例与乳牙列相关的复杂性成釉细胞瘤病例,也是印度人群中报道的最年轻的此类病例。