Bravo Bruna Souza Felix, Carvalho Raquel de Melo, Gallo Bruna Fanton, Bravo Leonardo Gonçalves
Bravo Clinic, Rio de Janeiro, RJ, Brazil.
J Cutan Aesthet Surg. 2021 Jan-Mar;14(1):88-92. doi: 10.4103/JCAS.JCAS_20_20.
Botulinum toxin type A injection remains the leading nonsurgical cosmetic procedure worldwide with a high rate of efficacy and patient satisfaction.
This study aims to demonstrate the importance of individualization of botulinum toxin doses to treat the upper face according to the age of the patients, considering the muscles particularities and the specificities of each face area.
A retrospective study with 389 female patients treated with botulinum toxin type A in the upper third of the face (forehead, glabellar, and periorbital lines). Statistical analysis of the data was performed.
The mean age was 47.49 years old and the median total dose of botulinum toxin type A was 53.76 units, whereas the median dose in the glabella was 26.28 U, the mean forehead dose was 12.23 U, and in the periorbital area was 14.79 U, adding both sides. It is possible to observe that the doses are negatively correlated with age, except in the periorbital area, where an increase in the dose was observed.
It is important to highlight that although there is consensus on pre-established dose suggestions, the treatment should be individualized, respecting the individual characteristics of each patient.
A型肉毒毒素注射仍然是全球领先的非手术美容程序，具有很高的疗效和患者满意度。
本研究旨在证明根据患者年龄、肌肉特点和每个面部区域的特异性，个体化确定A型肉毒毒素剂量以治疗上半脸的重要性。
对389例在上半脸（额头、眉间和眶周纹）接受A型肉毒毒素治疗的女性患者进行回顾性研究。对数据进行统计分析。
平均年龄为47.49岁，A型肉毒毒素的总剂量中位数为53.76单位，而眉间的剂量中位数为26.28单位，额头平均剂量为12.23单位，眶周区域两侧相加为14.79单位。可以观察到，除眶周区域剂量增加外，其他剂量与年龄呈负相关。
必须强调的是，尽管对于预先确定的剂量建议已达成共识，但治疗仍应个体化，尊重每位患者的个体特征。
