Wang Chaoyu, Gong Yi, Jiang Qingming, Liang Xiping, Chen Rui
Department of Hematology-Oncology Chongqing Key Laboratory of Translational Research for Cancer Metastasis and Individualized Treatment Chongqing University Cancer Hospital Chongqing China.
Department of Pathology Chongqing Key Laboratory of Translational Research for Cancer Metastasis and Individualized Treatment Chongqing University Cancer Hospital Chongqing China.
Clin Case Rep. 2021 May 5;9(5):e04083. doi: 10.1002/ccr3.4083. eCollection 2021 May.
Angioimmunoblastic T-cell lymphoma (AITL) is the subtype of mature T-cell non-Hodgkin lymphoma. Compared with diffuse large B-cell lymphoma (DLBCL), AITL patients are frequently accompanied with Epstein-Barr virus (EBV) infection. To date, there is no report on the subsequent development of AITL in patients with EBV-positive DLBCL. We performed a rare case of EBV-positive AITL developing one year after initial diagnosis of EBV-positive DLBCL. The patient showed poor response to the chemotherapy regimen, and poor survival.
血管免疫母细胞性T细胞淋巴瘤（AITL）是成熟T细胞非霍奇金淋巴瘤的亚型。与弥漫性大B细胞淋巴瘤（DLBCL）相比，AITL患者常伴有EB病毒（EBV）感染。迄今为止，尚无关于EBV阳性DLBCL患者继发AITL的报道。我们报告了1例罕见的病例，该患者在初诊为EBV阳性DLBCL 1年后发生了EBV阳性AITL。该患者对化疗方案反应不佳，生存期较短。
