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社会经济地位对原发性全髋关节置换术后 90 天和 365 天翻修率和死亡率的影响:一项基于丹麦全国数据库中 103901 例骨关节炎患者的队列研究。

Impact of socioeconomic status on the 90- and 365-day rate of revision and mortality after primary total hip arthroplasty: a cohort study based on 103,901 patients with osteoarthritis from national databases in Denmark.

机构信息

Department of Clinical Epidemiology, Aarhus University Hospital.

Department of Orthopaedic Surgery, Lillebaelt Hospital-Vejle, and Department of Regional Health Research, University of Southern Denmark.

出版信息

Acta Orthop. 2021 Oct;92(5):581-588. doi: 10.1080/17453674.2021.1935487. Epub 2021 Jun 4.

Abstract
  • Socioeconomic inequality in health is recognized as an important public health issue. We examined whether socioeconomic status (SES) is associated with revision and mortality rates after total hip arthroplasty (THA) within 90 and 365 days. - We obtained SES markers (cohabitation, education, income, and liquid assets) on 103,901 THA patients from Danish health registers (year 1995-2017). The outcomes were any revision (all revisions), specified revision (due to infection, fracture, or dislocation), and mortality. We used Cox regression analysis to estimate adjusted hazard ratio (aHR) of each outcome with 95% confidence interval (CI) for each SES marker. - Within 90 days, the aHR for any revision was 1.3 (95% CI 1.1-1.4) for patients living alone vs. cohabiting. The aHR was 2.0 (CI 1.4-2.6) for low-income vs. high-income among patients < 65 years. The aHR was 1.2 (CI 0.9-1.7) for low liquid assets among patients > 65 years. Results were consistent for any revision within 365 days as well as for revisions due to infection, fracture, and dislocation. The aHR for mortality was 1.4 (CI 1.2-1.6) within 90 days and 1.3 (CI 1.2-1.5) within 365 days for patients living alone vs. cohabiting. Low education, low income, and low liquid assets were associated with increased mortality rate within both 90 and 365 days. - Our results suggest that living alone, low income, and low liquid assets were associated with increased revision and mortality up to 365 days after THA surgery. Optimizing medical conditions prior to surgery and implementing different post-THA support strategies with a focus on vulnerable patients may reduce complications associated with inequality.
摘要

社会经济地位不平等是一个重要的公共卫生问题。本研究旨在探讨社会经济地位(SES)与全髋关节置换术(THA)后 90 天和 365 天内的翻修率和死亡率之间的关系。

我们从丹麦健康登记处获取了 103901 例 THA 患者的 SES 标志物(同居、教育、收入和流动资产)(1995 年至 2017 年)。结局指标包括任何翻修(所有翻修)、特定翻修(感染、骨折或脱位)和死亡率。我们使用 Cox 回归分析估计了每个 SES 标志物的调整后的危险比(aHR)及其 95%置信区间(CI)。

在 90 天内,与同居患者相比,独居患者的任何翻修的 aHR 为 1.3(95%CI 1.1-1.4)。在<65 岁的患者中,低收入与高收入患者的 aHR 为 2.0(CI 1.4-2.6)。在>65 岁的患者中,低流动资产的 aHR 为 1.2(CI 0.9-1.7)。在 365 天内的任何翻修、感染、骨折和脱位的翻修中,结果均一致。独居患者与同居患者相比,90 天内的死亡率 aHR 为 1.4(95%CI 1.2-1.6),365 天内的死亡率 aHR 为 1.3(95%CI 1.2-1.5)。低教育程度、低收入和低流动资产与 90 天和 365 天内的死亡率升高相关。

本研究结果表明,独居、低收入和低流动资产与 THA 术后 365 天内的翻修和死亡率升高有关。在手术前优化患者的医疗状况,并实施针对弱势患者的不同 THA 后支持策略,可能会降低与不平等相关的并发症。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ea8f/8519516/3483e4e92583/IORT_A_1935487_F0002_C.jpg

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