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夏季进行的全髋关节置换术与因人工关节感染导致的翻修风险增加无关:一项对丹麦髋关节置换登记处58449例骨关节炎患者的队列研究。

Total hip arthroplasty performed in summer is not associated with increased risk of revision due to prosthetic joint infection: a cohort study on 58 449 patients with osteoarthritis from the Danish Hip Arthroplasty Register.

作者信息

Joanroy Rajzan, Møller Jens Kjølseth, Gubbels Sophie, Overgaard Søren, Varnum Claus

机构信息

Department of Orthopaedic Surgery, Lillebaelt Hospital, Vejle, Denmark.

Department of Regional Health Research, University of Southern Denmark, Odense, Denmark.

出版信息

J Bone Jt Infect. 2024 Jan 23;9(1):1-8. doi: 10.5194/jbji-9-1-2024. eCollection 2024.

Abstract

: Danish surveillance data indicated a higher risk of revision due to prosthetic joint infection (PJI) following total hip arthroplasty (THA) performed during the summer season. We investigated the association between summer and revision risk following primary THA. : This study identified 58 449 patients from the Danish Hip Arthroplasty Register (DHR) with unilateral primary THA due to osteoarthritis from 2010-2018. From Danish Health Registries, we retrieved information on Charlson Comorbidity Index (CCI), immigration, and death and microbiological data on intraoperative biopsies and cohabitation status. Meteorological data were received from the Danish Meteorological Institute. Summer was defined as June-September, and THAs performed during October-May were used as controls. The primary outcome was revision due to PJI: the composite of revision with culture-positive biopsies or reported PJI to the DHR. The secondary outcome was any revision. The cumulative incidences of revision and the corresponding adjusted relative risk (RR) with 95 % confidence intervals (CI) were calculated by season of the primary THA. : A total of 1507 patients were revised, and 536 were due to PJI. The cumulative incidence for THAs performed during summer and the rest of the year was 1.1 % (CI 1.0-1.3) and 1.1 % (CI 1.0-1.2) for PJI revision and 2.7 % (CI 2.5-3.0) and 2.5 % (CI 2.4-2.7) for any revision, respectively. The adjusted RR for THAs performed during summer vs. the rest of the year for PJI revision and any revision was 1.1 (CI 0.9-1.3) and 1.1 (CI 1.0-1.2), respectively. : We found no association between summer and the risk of PJI revision or any revision in a northern European climate.

摘要

丹麦的监测数据表明,在夏季进行全髋关节置换术(THA)后,因假体关节感染(PJI)进行翻修的风险更高。我们调查了初次THA后夏季与翻修风险之间的关联。

本研究从丹麦髋关节置换登记处(DHR)中识别出2010年至2018年因骨关节炎接受单侧初次THA的58449例患者。我们从丹麦健康登记处获取了关于Charlson合并症指数(CCI)、移民、死亡以及术中活检的微生物学数据和同居状况的信息。气象数据来自丹麦气象研究所。夏季定义为6月至9月,10月至5月进行的THA用作对照。主要结局是因PJI进行翻修:活检培养阳性或向DHR报告的PJI进行翻修的综合情况。次要结局是任何翻修。根据初次THA的季节计算翻修的累积发生率以及相应的调整相对风险(RR)和95%置信区间(CI)。

共有1507例患者进行了翻修,其中536例是由于PJI。夏季和一年中其他时间进行的THA因PJI翻修的累积发生率分别为1.1%(CI 1.0 - 1.3)和1.1%(CI 1.0 - 1.2),任何翻修的累积发生率分别为2.7%(CI 2.5 - 3.0)和2.5%(CI 2.4 - 2.7)。夏季与一年中其他时间进行的THA因PJI翻修和任何翻修的调整RR分别为1.1(CI 0.9 - 1.3)和1.1(CI 1.0 - 1.2)。

我们发现在北欧气候下,夏季与PJI翻修风险或任何翻修风险之间没有关联。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8b0c/11002913/a67b19e534a8/jbji-9-1-f01.jpg

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