药品安全委员会关于口服避孕药与抗惊厥药和抗生素药物相互作用的黄卡报告评估。
Evaluation of Committee on Safety of Medicines yellow card reports on oral contraceptive-drug interactions with anticonvulsants and antibiotics.
作者信息
Back D J, Grimmer S F, Orme M L, Proudlove C, Mann R D, Breckenridge A M
机构信息
Department of Pharmacology and Therapeutics, University of Liverpool.
出版信息
Br J Clin Pharmacol. 1988 May;25(5):527-32. doi: 10.1111/j.1365-2125.1988.tb03341.x.
Abstract
- We have searched the adverse reactions register for the years 1968-84 in an attempt to evaluate data relating to reported pregnancies in women on oral contraceptive steroids (OCS) who concurrently received either an antiepileptic drug or an antibiotic. 2. A total of 43 pregnancies were reported in women on OC therapy who concurrently received antiepileptic drugs and 63 pregnancies in women receiving antibiotics. In addition the number of prescriptions for both antiepileptics and antibiotics in England are reported for the years 1973-84.
摘要
- 我们检索了1968年至1984年的不良反应登记册，试图评估与同时服用抗癫痫药物或抗生素的口服避孕药类固醇（OCS）女性的妊娠报告相关的数据。2. 报告显示，接受OC治疗并同时服用抗癫痫药物的女性共有43例妊娠，接受抗生素治疗的女性有63例妊娠。此外，还报告了1973年至1984年英格兰抗癫痫药物和抗生素的处方数量。
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