Hahn P, Taller M, Chan H
Department of Obstetrics, University of British Columbia, Vancouver, Canada.
Biol Neonate. 1988;53(6):362-6. doi: 10.1159/000242814.
The activities of glutaminase and glutamate dehydrogenase in the small intestinal mucosa of infant rats were found to increase at the time of weaning. Pyruvate carboxylase activity, on the other hand, was very high during the suckling period and decreased to negligible values at weaning. It is suggested that gluconeogenesis in the infant mucosa occurs primarily via oxaloacetate and not via alpha-ketoglutarate.
研究发现，幼鼠小肠黏膜中的谷氨酰胺酶和谷氨酸脱氢酶活性在断奶时会增加。另一方面，丙酮酸羧化酶活性在哺乳期间非常高，在断奶时降至可忽略不计的值。有人提出，婴儿黏膜中的糖异生主要通过草酰乙酸而非α-酮戊二酸进行。
