Bioprocessing and Biodetection Lab (BBL), Department of Food Science & Technology, Faculty of Agricultural Engineering and Technology, University of Tehran, PO Box 4111, Karaj 31587-77871, Iran.
Pharmaceutical Technology Laboratory, Drug Applied Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Food Chem. 2021 Nov 15;362:130040. doi: 10.1016/j.foodchem.2021.130040. Epub 2021 May 11.
This study aimed at the fabrication of licorice extract (LE)-loaded microparticles by complex coacervation, using chickpea protein isolate (CPI) and soluble fraction of Persian gum (SFPG). The LE-loaded microparticles with the highest encapsulation efficiency (97.87%) and loading capacity (11.35%) were obtained at pH 3 and CPI: SFPG ratio, core: coating ratio, and polymer concentration of 2, 1.5, and 2, respectively. The LE-loaded microparticles (2-15 μm) possessed heterogeneous microstructure, and the Fourier-transform infrared spectroscopy data confirmed the pronounced effect of electrostatic interactions and hydrogen bonding. The thermostability, amorphous structure, and color of the LE-loaded microparticles were significantly enhanced, compared to free LE. The sensory evaluation of the model beverages containing LE-loaded microparticles revealed that the microencapsulation was able to mask the bitter aftertaste and color of the extract. Thus, the results of this research confirm the potential of CPI-SFPG complex coacervates for the efficient delivery of glycyrrhizin via incorporation into functional food products.
本研究旨在通过复凝聚法制备甘草提取物(LE)微球,使用鹰嘴豆分离蛋白(CPI)和刺梧桐胶可溶性部分(SFPG)。在 pH 3 时,获得了包封效率(97.87%)和载药量(11.35%)最高的 LE 载药微球,其 CPI:SFPG 比、芯材:包衣比和聚合物浓度分别为 2、1.5 和 2。LE 载药微球(2-15μm)具有不均匀的微观结构,傅里叶变换红外光谱数据证实了静电相互作用和氢键的显著影响。与游离 LE 相比,LE 载药微球的热稳定性、无定形结构和颜色得到了显著提高。含有 LE 载药微球的模型饮料的感官评价表明,微胶囊化能够掩盖提取物的苦味和颜色。因此,本研究结果证实了 CPI-SFPG 复凝聚物在通过功能性食品产品有效递送甘草酸方面的潜力。