The role of the SARS-CoV-2 envelope protein as a pH-dependent cation channel.
作者信息
Trobec Tomaž
机构信息
Institute of Preclinical Sciences, Veterinary Faculty, University of Ljubljana, Gerbičeva 60, Ljubljana, 1000, Slovenia.
出版信息
J Physiol. 2021 Jul;599(14):3435-3436. doi: 10.1113/JP281785. Epub 2021 Jun 24.
Abstract
摘要
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本文引用的文献
1
The envelope protein of SARS-CoV-2 increases intra-Golgi pH and forms a cation channel that is regulated by pH.SARS-CoV-2 的包膜蛋白会增加高尔基体腔内的 pH 值，并形成一个受 pH 值调节的阳离子通道。
J Physiol. 2021 Jun;599(11):2851-2868. doi: 10.1113/JP281037. Epub 2021 Mar 24.
2
Repurposed drugs and nutraceuticals targeting envelope protein: A possible therapeutic strategy against COVID-19.靶向包膜蛋白的药物和营养保健品的重新利用：一种对抗新冠病毒的可能治疗策略。
Genomics. 2021 Jan;113(1 Pt 2):1129-1140. doi: 10.1016/j.ygeno.2020.11.009. Epub 2020 Nov 13.
3
Coronavirus Proteins as Ion Channels: Current and Potential Research.冠状病毒蛋白作为离子通道：当前和潜在的研究。
Front Immunol. 2020 Oct 9;11:573339. doi: 10.3389/fimmu.2020.573339. eCollection 2020.
4
SARS-CoV-2 E protein is a potential ion channel that can be inhibited by Gliclazide and Memantine.SARS-CoV-2 棘突蛋白是一种潜在的离子通道，可被格列齐特和盐酸美金刚抑制。
Biochem Biophys Res Commun. 2020 Sep 10;530(1):10-14. doi: 10.1016/j.bbrc.2020.05.206. Epub 2020 Jun 20.
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Structural insight into the role of novel SARS-CoV-2 E protein: A potential target for vaccine development and other therapeutic strategies.新型 SARS-CoV-2 E 蛋白结构研究：疫苗开发和其他治疗策略的潜在靶点。
PLoS One. 2020 Aug 12;15(8):e0237300. doi: 10.1371/journal.pone.0237300. eCollection 2020.
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