Ogawa H, Hayama T, Yamashita Y
Department of Physiology, Kumamoto University Medical School, Japan.
Brain Res. 1988 Jun 28;454(1-2):321-31. doi: 10.1016/0006-8993(88)90833-5.
While stimulating the entire oral cavity of anesthetized rats, we recorded 3 types of neurons in the solitary tract nucleus; taste, mechanoreceptive and cold neurons. Most of the taste neurons were sensitive to thermal as well as to mechanical stimulations. Taste neurons predominantly sensitive to sucrose responded to warming and those most excited by NaCl or HCl were sensitive to cooling, and significant correlations were found between sucrose and warming and between NaCl and cooling. Most of the cold-sensitive taste neurons had receptive fields (RFs) at the anterior tongue and warm-sensitive taste neurons had whole or part of the RFs at the nasoincisor duct. About half the number of mechanoreceptive neurons were sensitive to cooling, producing phasic responses. RFs of some thermosensitive mechanoreceptive neurons and cold neurons were located. Warm-sensitive mechanoreceptive neurons or warm neurons were not evident. Therefore, interaction between thermal and taste sensations in the oral cavity probably takes place in the solitary tract nucleus, as well as in the chorda tympani.
在刺激麻醉大鼠的整个口腔时，我们在孤束核中记录到了3种类型的神经元：味觉神经元、机械感受神经元和冷觉神经元。大多数味觉神经元对热刺激和机械刺激都敏感。对蔗糖主要敏感的味觉神经元对升温有反应，而对氯化钠或盐酸最兴奋的那些味觉神经元对降温敏感，并且在蔗糖与升温之间以及氯化钠与降温之间发现了显著的相关性。大多数对冷敏感的味觉神经元在前舌有感受野（RFs），而对热敏感的味觉神经元在鼻切牙管有全部或部分感受野。约一半数量的机械感受神经元对降温敏感，产生相位反应。一些热敏机械感受神经元和冷觉神经元的感受野被定位。对热敏感的机械感受神经元或热觉神经元并不明显。因此，口腔中热觉与味觉之间的相互作用可能发生在孤束核以及鼓索中。
