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椎体前路拴系术治疗骨骼未成熟特发性脊柱侧凸:112 例结果。

Anterior Vertebral Body Tethering for Treatment of Idiopathic Scoliosis in the Skeletally Immature: Results of 112 Cases.

机构信息

British Columbia Children's Hospital, Vancouver, British Columbia, Canada.

Chu Sainte-Justine University Hospital, Montreal, Canada.

出版信息

Spine (Phila Pa 1976). 2021 Nov 1;46(21):1461-1467. doi: 10.1097/BRS.0000000000004061.

Abstract

STUDY DESIGN

Prospective case series.

OBJECTIVE

Determine the efficacy of anterior vertebral body tethering (AVBT) in skeletally immature patients.

SUMMARY OF BACKGROUND DATA

The value of AVBT is currently unclear given the paucity of available data.

METHODS

Consecutive skeletally immature patients with idiopathic scoliosis were treated with AVBT between 2012 and 2018 by one of two surgeons working at two independent centers and followed up for >2 years. Data were collected prospectively and supplemented retrospectively where necessary. Outcomes were measured preoperatively, at first erect radiograph (FE), 1-year postoperatively and at most recent follow up (FU).

RESULTS

One hundred twelve patients underwent 116 primary tethering procedures (108 thoracic and eight lumbar tethers). Four patients had primary tethering of both lumbar and thoracic curves. At surgery mean age was 12.7 ± 1.4 years (8.2-16.7) and Risser 0.5 ± 0.9 (0-3). Follow up was mean 37 ± 9 months (15-64). Preoperative mean coronal Cobb angle of the 130 tethered curves was 50.8° ± 10.2 (31-81) and corrected significantly to 26.6° ± 10.1 (-3-61) at FE radiograph (P < 0.001). Further significant improvement was seen from FE to 1-year, to mean 23.1° ± 12.4 (-37-57) (P < 0.001). There was a small but significant increase between 1-year and FU to 25.7° ± 16.3 (-32-58) (P < 0.001), which appeared to reflect tether breakage. Untethered minor curves were corrected from 31.0° ± 9.5 (3-57) to 20.3° ± 10.3 (0-52) at FU (P < 0.001). Rib hump was corrected from 14.1 ± 4.8 (0-26) to 8.8° ± 5.4 (0-22) at FU (P < 0.01). Twenty-five patients (22%) had 28 complications. Fifteen patients (13%) requiring 18 revision operations including six completed and one awaited fusions.

CONCLUSION

AVBT of immature cases is associated with satisfactory deformity correction in the majority of cases. However, complication and revision rates suggest the need for improved implants and patient selection. Long-term follow-up remains crucial to establish the true efficacy of this procedure.Level of Evidence: 3.

摘要

研究设计

前瞻性病例系列研究。

目的

确定在骨骼未成熟的患者中进行前路椎体束缚术(AVBT)的疗效。

背景资料摘要

鉴于目前可用数据有限,AVBT 的价值尚不清楚。

方法

由两位在两个独立中心工作的外科医生对 2012 年至 2018 年间的 112 例特发性脊柱侧凸骨骼未成熟患者进行连续前瞻性病例系列研究,并进行了超过 2 年的随访。数据是前瞻性收集的,并在必要时进行回顾性补充。术前、第一次直立位 X 线片(FE)、术后 1 年和最近随访时测量结果。

结果

116 例患者进行了 116 例原发性束缚术(108 例胸段和 8 例腰段束缚)。4 例患者同时行胸腰段原发性束缚。手术时平均年龄为 12.7±1.4 岁(8.2-16.7),Risser 征 0.5±0.9(0-3)。平均随访 37±9 个月(15-64)。术前 130 个受束缚的曲线上的冠状 Cobb 角平均为 50.8°±10.2(31-81),在 FE 片上显著矫正至 26.6°±10.1(-3-61)(P<0.001)。从 FE 到 1 年时进一步显著改善,平均为 23.1°±12.4(-37-57)(P<0.001)。在 1 年到随访时,有一个小但显著的增加,平均为 25.7°±16.3(-32-58)(P<0.001),这似乎反映了束缚的断裂。未束缚的小弯矫正至 20.3°±10.3(0-52)(P<0.001)。肋骨隆凸从 14.1±4.8(0-26)矫正至 8.8°±5.4(0-22)(P<0.01)。25 例患者(22%)出现 28 例并发症。15 例患者(13%)需要 18 次翻修手术,其中 6 例已完成,1 例仍在等待融合。

结论

AVBT 治疗骨骼未成熟患者可获得满意的畸形矫正,但并发症和翻修率表明需要改进植入物和患者选择。长期随访仍然是确定该手术真正疗效的关键。

证据水平

3 级。

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Anterior vertebral body tethering shows mixed results at 2-year follow-up.前路椎体固定术后随访 2 年,结果不一。
Spine Deform. 2021 Mar;9(2):481-489. doi: 10.1007/s43390-020-00226-x. Epub 2020 Oct 28.

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