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青少年特发性脊柱侧凸的前路椎体拴系术:我们最初十年的临床经验。

Anterior vertebral tethering for adolescent idiopathic scoliosis: our initial ten year clinical experience.

机构信息

Massachusetts General Hospital, Harvard Medical School, 55 Fruit St., Yawkey 3E, Boston, MA, 02114, USA.

Dartmouth Hitchcock Medical Center, Geisel School of Medicine at Dartmouth, Lebanon, NH, USA.

出版信息

Spine Deform. 2024 Sep;12(5):1355-1367. doi: 10.1007/s43390-024-00897-w. Epub 2024 May 26.

Abstract

BACKGROUND

Anterior vertebral tethering (AVT) is a minimally invasive alternative to fusion surgery for adolescent idiopathic scoliosis (AIS) that offers the potential for definitive scoliosis treatment with the possibility of preservation of the growth, motion, function and overall health of the spine. This study represents our first ten years using AVT to treat AIS.

METHODS

In this retrospective review we analyzed our first 74 AIS patients treated with AVT 2010-2020. Multiple Lenke curve types 33-70° were treated with skeletal maturity spanning Risser -1 to 5.

RESULTS

Of 74 consecutive AIS patients treated with AVT, 52 patients (47 female, 5 male) had sufficient 2-year follow-up for inclusion. Forty-six of these 52 patients (88%) with 65 curves (35T, 30TL/L) were satisfactorily treated with AVT demonstrating curve correction from 48.6° pre-op (range 33°-70°) at age 15.1 years (range 9.2-18.8) and skeletal maturity of Risser 2.8 (range -1 to 5) to 23.2° post-op (range 0°-54°) and 24.0° final (range 0°-49°) at 3.3 years follow-up (range 2-10 years). Curve corrections from pre-op to post-op and pre-op to final were both significant (p < 0.001). The 0.8° change from post-op to final was not significant but did represent good control of scoliosis correction over time. Thoracic kyphosis and lumbar lordosis were maintained in a normal range throughout while axial rotation demonstrated a slight trend toward improvement. Skeletal maturity of Risser 4 or greater was achieved in all but one patient. Four of the 52 patients (8%) required additional procedures for tether rupture (3 replacements) or overcorrection (1 removal) to achieve satisfactory treatment status after AVT. An additional 6 of the 52 patients (12%), however, were not satisfactorily treated with AVT, requiring fusion for overcorrection (2) or inadequate correction (4).

CONCLUSIONS

In this study, AIS was satisfactorily treated with AVT in the majority of patients over a broad range of curve magnitudes, curve types, and skeletal maturity. Though late revision surgery for overcorrection, inadequate correction, or tether rupture was not uncommon, the complication of overcorrection was eliminated after our first ten patients by a refinement of indications.

LEVEL OF EVIDENCE

IV.

摘要

背景

对于青少年特发性脊柱侧凸(AIS),前路椎体束缚(AVT)是一种微创的融合手术替代方法,具有明确治疗脊柱侧凸的潜力,同时有可能保留脊柱的生长、运动、功能和整体健康。本研究代表了我们使用 AVT 治疗 AIS 的第一个十年。

方法

在这项回顾性研究中,我们分析了 2010 年至 2020 年间使用 AVT 治疗的 74 例 AIS 患者。多个 Lenke 曲线类型 33-70°在骨骼成熟度跨越 Risser-1 至 5 时进行治疗。

结果

在接受 AVT 治疗的 74 例连续 AIS 患者中,有 52 例(47 例女性,5 例男性)有足够的 2 年随访结果纳入本研究。这 52 例中有 46 例(88%)的 65 个曲线(35T、30TL/L)接受了 AVT 的满意治疗,表明曲线从术前的 48.6°(范围 33°-70°)得到矫正,患者的年龄为 15.1 岁(范围 9.2-18.8),骨骼成熟度为 Risser 2.8(范围-1 至 5)至术后的 23.2°(范围 0°-54°)和 24.0°最终(范围 0°-49°),随访时间为 3.3 年(范围 2-10 年)。从术前到术后和术前到最终的曲线矫正均有显著差异(p<0.001)。从术后到最终的 0.8°变化虽然没有显著意义,但确实代表了随着时间的推移对脊柱侧凸矫正的良好控制。胸腰椎曲度在整个过程中均保持在正常范围内,轴向旋转显示出轻微改善的趋势。除 1 例患者外,所有患者的骨骼成熟度均达到 Risser 4 或更高水平。52 例患者中有 4 例(8%)需要进行额外的手术,以更换或移除(1 例)束缚带,以实现 AVT 治疗后的满意状态。然而,52 例患者中有 6 例(12%)的治疗效果不理想,需要融合以矫正过度(2 例)或矫正不足(4 例)。

结论

在这项研究中,AVT 可在广泛的曲线幅度、曲线类型和骨骼成熟度范围内,为大多数患者提供满意的 AIS 治疗效果。虽然晚期的矫形过度、矫正不足或束缚带断裂的修订手术并不少见,但在我们的前 10 例患者中,通过改进适应证,矫形过度的并发症得到了消除。

证据水平

IV。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/65be/11344032/f4bf69714f04/43390_2024_897_Fig1_HTML.jpg

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