Department of Gastrointestinal Endoscopy Unit, University of São Paulo School of Medicine, São Paulo 05403-010, Brazil.
World J Gastroenterol. 2021 May 28;27(20):2495-2506. doi: 10.3748/wjg.v27.i20.2495.
Acute post-endoscopic retrograde cholangiopancreatography pancreatitis (PEP) is a feared and potentially fatal complication that can be as high as up to 30% in high-risk patients. Pre-examination measures, during the examination and after the examination are the key to technical and clinical success with a decrease in adverse events. Several studies have debated on the subject, however, numerous topics remain controversial, such as the effectiveness of prophylactic medications and the amylase dosage time. This review was designed to provide an update on the current scientific evidence regarding PEP available in the literature.
急性内镜逆行胰胆管造影术后胰腺炎(PEP)是一种令人恐惧且潜在致命的并发症,在高危患者中发生率高达 30%。检查前、检查中和检查后的措施是技术和临床成功的关键,可以减少不良事件的发生。多项研究对此进行了探讨,但仍有许多问题存在争议,例如预防性药物的疗效和淀粉酶检测时间。本文旨在对目前文献中有关 PEP 的现有科学证据进行更新。