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髋关节置换术治疗髋关节破坏性化脓性关节炎的两阶段方案,不使用间隔器。

Total hip arthroplasty for destructive septic arthritis of the hip using a two-stage protocol without spacer placement.

机构信息

Department of Orthopaedic Surgery, Center for Musculoskeletal Surgery, Charité-Universitätsmedizin Berlin, Charitéplatz 1, 10117, Berlin, Germany.

出版信息

Arch Orthop Trauma Surg. 2023 Jan;143(1):19-28. doi: 10.1007/s00402-021-03981-2. Epub 2021 Jun 7.

Abstract

INTRODUCTION

The optimal treatment of patients with a degenerative joint disease secondary to an active or chronic septic arthritis of the hip is unclear. The aim of the present study was to report on our experience with two-stage total hip arthroplasty (THA) using a contemporary treatment protocol without spacer insertion.

MATERIALS AND METHODS

Our prospective institutional database was used to identify all patients with degenerative septic arthritis treated with a non-spacer two-stage protocol between 2011 and 2017. Clinical outcomes included interim revision, periprosthetic infection (PJI) and aseptic revision rates. Restoration of leg-length and offset were assessed radiographically. Modified Harris hip score (mHHS) were obtained. Treatment success was defined using the modified Delphi consensus criteria. Mean follow-up was 62 months (13-110).

RESULTS

A total of 33 patients with a mean age of 60 years (13-85) were included. 55% of the cohort was male and average Charlson Comorbidity Index (CCI) was 3.7 (0-12). 21 patients (64%) had an active/acute infection and 12 patients (36%) were treated for chronic/quiescent septic arthritis. Overall, 11 patients (33%) had treatment failure, including 5 patients who failed to undergo THA, 2 interim re-debridement for persistent infection, and 4 patients who developed PJI after an average of 7 months (0.3-13) following THA. The most common identified pathogen was Staphylococcus aureus (42.4%). No aseptic revision was recorded following THA. Leg-length and offset were successfully restored. Mean mHHS improved from 35.2 points to 73.4 points.

CONCLUSION

Two-stage THA without spacer placement is a viable treatment option for destructive septic arthritis of the hip, demonstrating comparable rates of infection control and functional outcome. However, definitive resection arthroplasty is not uncommon in these often critically ill patients.

摘要

引言

对于髋关节活动性或慢性化脓性关节炎继发退行性关节病患者,最佳治疗方法尚不清楚。本研究旨在报告我们使用无间隔体两期髋关节置换术(THA)治疗的经验,该方法采用了现代治疗方案,不使用间隔体。

材料和方法

我们使用前瞻性的机构数据库,确定了 2011 年至 2017 年期间采用非间隔体两期方案治疗的所有退行性化脓性关节炎患者。临床结果包括中期翻修、假体周围感染(PJI)和无菌性翻修率。评估了下肢长度和偏移的放射学恢复情况。获得改良 Harris 髋关节评分(mHHS)。采用改良 Delphi 共识标准定义治疗成功。平均随访时间为 62 个月(13-110)。

结果

共纳入 33 例患者,平均年龄为 60 岁(13-85)。55%的患者为男性,平均 Charlson 合并症指数(CCI)为 3.7(0-12)。21 例(64%)患者为活动性/急性感染,12 例(36%)患者为慢性/静止性化脓性关节炎。总体而言,11 例(33%)患者治疗失败,其中 5 例未能行 THA,2 例因持续感染行中期清创,4 例在 THA 后平均 7 个月(0.3-13)发生 PJI。最常见的病原体是金黄色葡萄球菌(42.4%)。THA 后无无菌性翻修。下肢长度和偏移得到成功恢复。平均 mHHS 从 35.2 分提高到 73.4 分。

结论

不使用间隔体的两期 THA 是髋关节破坏性化脓性关节炎的一种可行治疗选择,具有相似的感染控制和功能结果。然而,在这些经常患有重病的患者中,最终切除关节成形术并不少见。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1ddd/9886611/66114080c3a3/402_2021_3981_Fig1_HTML.jpg

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