Sección de Neurovascular, Servicio de Neurología, Hospital Universitario Miguel Servet, Zaragoza, Spain; Unidad de Neurointervencionismo, Servicio de Radiología, Hospital Universitario Miguel Servet, Zaragoza, Spain.
Instituto de Investigación Sanitaria Aragón (IIS Aragón), Zaragoza, Spain; Servicio de Neurología, Hospital Clínico Universitario Lozano Blesa, Zaragoza, Spain.
Neurologia (Engl Ed). 2021 Sep;36(7):531-536. doi: 10.1016/j.nrleng.2021.02.001. Epub 2021 Jun 5.
The COVID-19 pandemic has had an impact on ischaemic stroke management, with a reported decrease in hospital admissions, and even disruptions in healthcare and increased in-hospital mortality. However, there is a lack of evidence on the impact of the pandemic on functional prognosis. The aim of this study is to analyse the effect of the COVID-19 pandemic on the 3-month functional outcomes of patients hospitalised due to acute ischaemic stroke in Aragon (Spain).
We reviewed the data of all patients admitted due to ischaemic stroke to any hospital in our regional healthcare system between 30 December 2019 and 3 May 2020. We compared modified Rankin Scale scores and mortality at 3 months in patients hospitalised before and after the declaration of a state of emergency due to the COVID-19 pandemic.
In total, 318 patients with acute ischaemic stroke met our inclusion criteria. No differences were observed between periods in global or specific characteristics, with the exception of a higher proportion of patients older than 80 years during the first period (42.2% vs 29.0%, P = .028). In the comparative analysis, we found no significant differences in mortality (12.3 vs 7.9, P = .465) or in the proportion of patients with modified Rankin Scale scores ≤ 2 (57.7% vs 57.1%, P = .425) at 3 months.
To our knowledge, this is the first study to analyse the impact of COVID-19 pandemic on the 3-month functional outcomes of patients with ischaemic stroke. In our region, there has been no increase in rates of mortality or disability at 3 months in patients admitted due to ischaemic stroke during the pandemic.
COVID-19 大流行对缺血性脑卒中的管理产生了影响，据报道，医院收治人数减少，医疗服务甚至中断，住院死亡率增加。然而，目前缺乏大流行对功能预后影响的证据。本研究旨在分析 COVID-19 大流行对阿拉贡（西班牙）因急性缺血性脑卒中住院患者 3 个月功能结局的影响。
我们回顾了 2019 年 12 月 30 日至 2020 年 5 月 3 日期间因缺血性脑卒中入住我们区域医疗保健系统内任何一家医院的所有患者的数据。我们比较了在宣布 COVID-19 大流行紧急状态之前和之后因缺血性脑卒中住院的患者在 3 个月时的改良 Rankin 量表评分和死亡率。
共纳入 318 例急性缺血性脑卒中患者。两个时期在总体或具体特征方面无差异，除了第一个时期 80 岁以上患者的比例较高（42.2% vs 29.0%，P =.028）。在对比分析中，我们发现 3 个月时死亡率（12.3% vs 7.9%，P =.465）或改良 Rankin 量表评分≤2 的患者比例（57.7% vs 57.1%，P =.425）无显著差异。
据我们所知，这是第一项分析 COVID-19 大流行对缺血性脑卒中患者 3 个月功能结局影响的研究。在我们的地区，因缺血性脑卒中住院的患者在大流行期间，3 个月时的死亡率或残疾率没有增加。
