Suppr超能文献

宫颈癌长期生存者的生活质量:一项横断面研究。

Quality of life in long term survivors of cervical cancer: A cross sectional study.

机构信息

Department of Gynecological Oncology, Tata Memorial Centre, Homi Bhabha National University, Mumbai, Maharashtra, India.

Department of Biostatistics and Clinical Research Methodology, Tata Memorial Centre, Homi Bhabha National University, Mumbai, Maharashtra, India.

出版信息

Indian J Cancer. 2021 Apr-Jun;58(2):171-178. doi: 10.4103/ijc.IJC_712_18.

Abstract

BACKGROUND

Quality of life (QOL) is an important parameter to evaluate and modify in patients treated for cervical cancer as long-term survival is excellent in early-stage and reasonably good in locally advanced stage compared to other solid cancers. The aim of the study was the cross sectional evaluation of the quality of life in survivors completing at least 3 years of follow-up after curative therapy for cervical cancer at a tertiary cancer institute.

METHODS

All patients, following primary curative treatment with no evidence of recurrence and completing at least 3 years follow-up, were assessed for QOL using the European Organization for Research and Treatment of Cancer (EORTC) Quality of Life Questionnaire (QLQ)-30 and its cervical cancer module (Cx24). Patients were subdivided based on the modality of treatment. Analysis was done using Kruskal-Wallis and Mann-Whitney U test.

RESULTS

One hundred seven patients were analyzed out of the 113 patients initially included. Treated patients showed good global QOL (mean value: 84.07) and functional scores (covering all domains). In the cervical cancer module, sexual activity, sexual enjoyment, and sexual function were low in the majority of the respondents. Chronic lymphedema, symptom experience, and sexual worry were significant across all the treatment arms.

CONCLUSION

Cervical cancer survivors have an overall good QOL. However, certain concerns related to the sexual quality of life, symptom experience, and chronic lymphedema need to be addressed appropriately.

摘要

背景

生活质量(QOL)是评估和改善接受宫颈癌治疗患者的一个重要参数,因为与其他实体癌相比,早期宫颈癌患者的长期生存率非常高,局部晚期宫颈癌患者的生存率也相当可观。本研究旨在对在三级癌症研究所接受宫颈癌根治性治疗后至少随访 3 年的幸存者进行生活质量的横断面评估。

方法

所有在没有复发证据并完成至少 3 年随访的初治患者,使用欧洲癌症研究与治疗组织(EORTC)生活质量问卷(QLQ)-30 及其宫颈癌模块(Cx24)评估 QOL。患者根据治疗方式进行细分。采用 Kruskal-Wallis 和 Mann-Whitney U 检验进行分析。

结果

从最初纳入的 113 例患者中分析了 107 例。治疗组患者的总体 QOL(平均 84.07)和功能评分(涵盖所有领域)较好。在宫颈癌模块中,大多数患者的性活动、性享受和性功能较低。在所有治疗组中,慢性淋巴水肿、症状体验和性担忧都是显著的。

结论

宫颈癌幸存者的总体生活质量良好。然而,需要适当解决某些与性健康相关的问题、症状体验和慢性淋巴水肿等问题。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验