Clinical Pharmacy Center, Department of Pharmacy, Zhejiang Provincial People's Hospital, Affiliated People's Hospital, Hangzhou Medical College, Hangzhou, China.
Department of Pharmacy, Geriatric Care Hospital Zhejiang, Hangzhou, China.
J Diabetes Investig. 2021 Dec;12(12):2267-2270. doi: 10.1111/jdi.13611. Epub 2021 Jul 5.
Subcutaneous insulin resistance syndrome caused by obesity, induration at the injection site, skin temperature and other factors is common clinically, whereas resistance events caused by edema are relatively rare. This article introduced a case of a woman with type 2 diabetes mellitus with heart failure edema. Her blood glucose control was significantly associated with the level of edema. Excluding other factors, it can be concluded that edema might lead to subcutaneous insulin resistance syndrome, even if the edema at the injection site is not obvious.
肥胖、注射部位硬结、皮肤温度等因素引起的皮下胰岛素抵抗综合征在临床上较为常见,而由水肿引起的抵抗事件则相对较少。本文介绍了 1 例心力衰竭伴水肿的 2 型糖尿病女性患者,其血糖控制与水肿程度密切相关。排除其他因素,可推断水肿可能导致皮下胰岛素抵抗综合征,即使注射部位水肿不明显。