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基于再生和干细胞的面部年轻化技术。

Regenerative and stem cell-based techniques for facial rejuvenation.

机构信息

Department of Surgery, Division of Plastic Surgery, UC San Diego School of Medicine, San Diego, CA 92103-8890.

出版信息

Exp Biol Med (Maywood). 2021 Aug;246(16):1829-1837. doi: 10.1177/15353702211020701. Epub 2021 Jun 8.

DOI:10.1177/15353702211020701
PMID:34102897
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8381699/
Abstract

This review discusses the most novel ideas and modalities being incorporated into facial rejuvenation. Recent innovative techniques include the use of regenerative stem cell techniques and regeneration supportive modalities such as nano-technology or gene therapies. This review aims to investigate approaches that are less well known and lacking established evidence in order to proactively study these techniques prior to them becoming popularized. These applications and relevant research were reviewed in the context of both surgical and non-surgical modalities in clinical practice. Future directions include the concept of "precision cosmetic medicine" utilizing gene editing and cellular therapies to tailor rejuvenation techniques based on each individual's genetic make-up and therefore needs.

摘要

本文讨论了最新的面部年轻化理念和方法。最近的创新技术包括使用再生干细胞技术和再生支持模式,如纳米技术或基因疗法。本综述旨在研究那些不太知名且缺乏既定证据的方法,以便在这些技术普及之前对其进行前瞻性研究。这些应用和相关研究在临床实践中的手术和非手术方式方面进行了综述。未来的发展方向包括“精准美容医学”的概念,利用基因编辑和细胞疗法,根据每个人的基因构成和需求,定制个性化的年轻化技术。

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2
Targeting Alternative Splicing for Reversal of Cellular Senescence in the Context of Aesthetic Aging.靶向剪接以逆转美容性衰老背景下的细胞衰老。
Plast Reconstr Surg. 2021 Jan 1;147(1S-2):25S-32S. doi: 10.1097/PRS.0000000000007618.
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Send in the senolytics.送上衰老细胞溶解剂。
Nat Biotechnol. 2020 Dec;38(12):1371-1377. doi: 10.1038/s41587-020-00750-1.
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Fat Therapeutics: The Clinical Capacity of Adipose-Derived Stem Cells and Exosomes for Human Disease and Tissue Regeneration.脂肪疗法:脂肪来源干细胞和外泌体对人类疾病及组织再生的临床作用
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Prospective application of exosomes derived from adipose-derived stem cells in skin wound healing: A review.脂肪来源干细胞外泌体在皮肤伤口愈合中的前瞻性应用:综述
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