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胃和盲肠发生的异时性散发性硬纤维瘤病肿瘤

Metachronous Sporadic Desmoid Tumors Arisen in the Stomach and the Cecum.

作者信息

Tamaki Ichiro, Takahara Hidenori

机构信息

Department of Surgery, Ako City Hospital, Ako City, JPN.

出版信息

Cureus. 2021 May 4;13(5):e14847. doi: 10.7759/cureus.14847.

Abstract

Desmoid-type fibromatosis (DF) is a rare soft-tissue tumor demonstrating fibroblastic to myofibroblastic differentiation, recognized as a biologically intermediate, locally aggressive tumor; however, it can be clinically lethal due to its infiltrative growth and risk of locoregional recurrence. Desmoid-type fibromatoses can arise from any part of the body, however, intra-abdominal DFs comprise only 8% of all DFs. We report a case of a male in his 60s who presented with the metachronous occurrence of DF: gastric DF followed by cecal DF with two years of clinical interval. The latter tumor (cecal DF) developed under scheduled postoperative surveillance of laparoscopic gastrectomy. Although a surgical wound is known to be an inductive factor for DFs, the cecal DF developed in a part that was not a surgical site in the previous operation. Curative resection is the first treatment option when the tumor shows progression in size. Following the curative resection, close observation should be provided because of the risk of locoregional recurrence.

摘要

韧带样型纤维瘤病(DF)是一种罕见的软组织肿瘤,表现为成纤维细胞向肌成纤维细胞分化,被认为是一种生物学上介于中间型、局部侵袭性的肿瘤;然而,由于其浸润性生长和局部区域复发风险,它在临床上可能是致命的。韧带样型纤维瘤病可发生于身体的任何部位,不过,腹腔内DF仅占所有DF的8%。我们报告一例60多岁男性患者,其出现了DF的异时性发病:先出现胃DF,两年后出现盲肠DF,临床间隔期为两年。后一种肿瘤(盲肠DF)是在腹腔镜胃切除术后的定期监测中发生的。虽然手术切口已知是DF的诱导因素,但盲肠DF发生在先前手术的非手术部位。当肿瘤大小出现进展时,根治性切除是首选治疗方案。根治性切除后,由于存在局部区域复发风险,应进行密切观察。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/058d/8175913/cc5560518442/cureus-0013-00000014847-i01.jpg

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