Fagan K, Wilkinson I, Allen M, Brownlea S
Cytogenetics Laboratory, Newcastle Mater Misericordiae Hospital, Waratah, N.S.W., Australia.
Hum Genet. 1988 Aug;79(4):365-7. doi: 10.1007/BF00282178.
Cytogenetic and coagulation studies have been performed on two patients with different abnormalities of chromosome 8, i.e. del(8p23.1----pter) and dup(8q23.1----qter). Results confirm the existence of a regulatory mechanism for clotting factor VII on chromosome 8 and define its location to the p23.1----p23.2 region.
已对两名患有不同8号染色体异常(即del(8p23.1----pter)和dup(8q23.1----qter))的患者进行了细胞遗传学和凝血研究。结果证实8号染色体上存在凝血因子VII的调控机制,并将其定位到p23.1----p23.2区域。