Division of Overdose Prevention, National Center for Injury Prevention and Control, Centers for Disease Control and Prevention, Atlanta, GA.
Division of Overdose Prevention, National Center for Injury Prevention and Control, Centers for Disease Control and Prevention, Atlanta, GA; Oak Ridge Institute for Science and Education (ORISE), Oak Ridge, TN.
Ann Epidemiol. 2021 Oct;62:43-50. doi: 10.1016/j.annepidem.2021.05.008. Epub 2021 Jun 6.
Emergency department syndromic surveillance and hospital discharge data have been used to detect and monitor nonfatal drug overdose, yet few studies have assessed the differences and similarities between these two data sources.
The Centers for Disease Control and Prevention Drug Overdose Surveillance and Epidemiology system data from 14 states were used to compare these two sources at estimating monthly overdose burden and trends from January 2018 through December 2019 for nonfatal all drug, opioid-, heroin-, and stimulant-involved overdoses.
Compared to discharge data, syndromic data captured 13.3% more overall emergency department visits, 67.8% more all drug overdose visits, 15.6% more opioid-involved overdose visits, and 78.8% more stimulant-involved overdose visits. Discharge data captured 18.9% more heroin-involved overdoses. Significant trends were identified for all drug (Average Monthly Percentage Change [AMPC]=1.1, 95% CI=0.4,1.8) and stimulant-involved overdoses (AMPC=2.4, 95% CI=1.2,3.7) in syndromic data; opioid-involved overdoses increased in both discharge and syndromic data (AMPC=0.9, 95% CI=0.2,1.7; AMPC=1.9, CI=1.1,2.8).
Results demonstrate that discharge data may be better for reporting counts, yet syndromic data are preferable to detect changes quickly and to alert practitioners and public health officials to local overdose clusters. These data sources do serve complementary purposes when examining overdose trends.
急诊部门综合征监测和医院出院数据已被用于检测和监测非致命性药物过量情况,但很少有研究评估这两种数据源之间的差异和相似之处。
利用疾病控制与预防中心药物过量监测和流行病学系统来自 14 个州的数据,比较了这两种来源,以评估 2018 年 1 月至 2019 年 12 月期间非致命性所有药物、阿片类药物、海洛因和兴奋剂药物过量的每月负担和趋势。
与出院数据相比,综合征数据捕捉到的急诊部门就诊总人数增加了 13.3%,所有药物过量就诊人数增加了 67.8%,阿片类药物过量就诊人数增加了 15.6%,兴奋剂药物过量就诊人数增加了 78.8%。出院数据捕捉到的海洛因药物过量就诊人数增加了 18.9%。综合征数据中所有药物(平均每月百分比变化 [AMPC]=1.1,95%置信区间[CI]=0.4,1.8)和兴奋剂药物过量(AMPC=2.4,95%CI=1.2,3.7)都有显著的趋势;在出院数据和综合征数据中,阿片类药物药物过量都在增加(AMPC=0.9,95%CI=0.2,1.7;AMPC=1.9,CI=1.1,2.8)。
结果表明,出院数据可能更适合报告计数,但综合征数据更适合快速检测变化,并提醒从业者和公共卫生官员注意当地的药物过量集群。在检查药物过量趋势时,这两种数据源确实具有互补作用。