Periumbilical perforating pseudoxanthoma elasticum.

Perforating pseudoxanthoma elasticum is a rare disorder that can occur in skin lesions associated with hereditary pseudoxanthoma elasticum and as a localized acquired cutaneous form. The localized lesion usually occurs in a periumbilical location in obese, multiparous black women. Here we report an additional case of periumbilical perforating pseudoxanthoma elasticum and discuss its potential relationship to systemic disease (hereditary pseudoxanthoma elasticum).