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骶骨脂肪形成性孤立性纤维性肿瘤:一例报告及文献复习

Fat-forming solitary fibrous tumor of the sacrum: A case report and literature review.

作者信息

Furuta Toshihiro, Nakai Yudai, Gonoi Wataru, Kurokawa Ryo, Okimoto Naomasa, Sakamoto Naoya, Fukuchi Haruyuki, Kobayashi Hiroshi, Makise Naohiro, Abe Osamu

机构信息

Department of Radiology, Graduate School of Medicine, The University of Tokyo, Hongo 7-3-1, Bunkyo-ku, Tokyo 113-8655, Japan.

Department of Orthopaedic Surgery, Graduate School of Medicine, The University of Tokyo, Hongo 7-3-1, Bunkyo-ku, Tokyo 113-8655, Japan.

出版信息

Radiol Case Rep. 2021 May 25;16(7):1874-1877. doi: 10.1016/j.radcr.2021.04.052. eCollection 2021 Jul.

Abstract

Fat-forming variant of solitary fibrous tumor (SFT) is a rare mesenchymal neoplasm. Here we report the case of a 33-year-old woman who developed pain and muscle weakness from the posterior aspect of the right hip to lower extremity. Imaging examinations revealed a mass with fatty components and hypervascular solid components filling the sacral spinal canal and sacral foramen. The sacral mass was resected and histological examination of the specimens revealed patternless proliferation of short spindle-shaped cells with staghorn blood vessels. A number of mature adipocyte-like cells were also observed. The tumor cells were positive for STAT6 and the nuclei of the adipocytes were also positive, which was diagnostic for fat-forming SFT.

摘要

孤立性纤维瘤(SFT)的脂肪形成变体是一种罕见的间叶性肿瘤。在此,我们报告一例33岁女性病例,该患者从右髋后部至下肢出现疼痛和肌肉无力无力影像学{"name":"GodelPlugin","parameters":{"input":"乱码"}}]乱码]无力。影像学检查显示一个肿块,具有脂肪成分和填充骶管及骶孔的高血管实性成分。切除骶部肿块,对标本进行组织学检查显示短梭形细胞无规律增殖,伴有鹿角状血管。还观察到许多成熟的脂肪细胞样细胞。肿瘤细胞STAT6呈阳性,脂肪细胞核也呈阳性,这对脂肪形成性SFT具有诊断意义。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b644/8170013/72f4df2dc9a2/gr1.jpg

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