Eudowood Division of Pediatric Respiratory Sciences, Johns Hopkins School of Medicine, Baltimore, MD, USA.
Division of Pulmonary and Sleep, Children's Hospital of Philadelphia, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Expert Rev Respir Med. 2021 Oct;15(10):1271-1279. doi: 10.1080/17476348.2021.1941886. Epub 2021 Jun 17.
: Environmental factors play a critical role in the progression or resolution of chronic respiratory diseases. However, studies are limited on the impact of environmental risk factors on individuals born prematurely with lung disease after they leave the neonatal intensive care unit and are discharged into the home environment.: In this review, we cover current knowledge of environmental exposures that impact outcomes of preterm respiratory disease, including air pollution, infections, and disparities. The limited data do suggest that certain exposures should be avoided and there are potential preventative strategies for other exposures. There is a need for additional research outside the neonatal intensive care unit that focuses on individual and community-level factors that affect long-term outcomes.: Preterm respiratory disease can impose a significant burden on infants, children, and young adults born prematurely, but may improve for many individuals over time. In this review, we outline the exposures that may potentially hasten, delay, or prevent resolution of lung injury in preterm children.
环境因素在慢性呼吸道疾病的进展或缓解中起着关键作用。然而,关于环境风险因素对离开新生儿重症监护病房并出院到家庭环境后的患有肺部疾病的早产儿的影响的研究有限。在这篇综述中,我们涵盖了当前关于影响早产儿呼吸疾病结局的环境暴露的知识,包括空气污染、感染和差异。有限的数据确实表明,某些暴露应该避免,而对于其他暴露,可能存在潜在的预防策略。除了新生儿重症监护室外,还需要进行更多的研究,重点关注影响长期结局的个体和社区因素。早产儿呼吸疾病会给早产儿出生的婴儿、儿童和年轻人带来重大负担,但随着时间的推移,许多人的病情可能会好转。在这篇综述中,我们概述了可能加速、延迟或预防早产儿肺损伤缓解的暴露因素。