Henan Human Sperm Bank, The Third Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Department of Clinical Laboratory, The Third Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Front Public Health. 2023 Aug 3;11:1219340. doi: 10.3389/fpubh.2023.1219340. eCollection 2023.
Air pollution may impair male fertility, but it remains controversial whether air pollution affects semen quality until now.
We undertake a meta-analysis to explore potential impacts of six pollutants exposure during the entire window (0-90 days prior to ejaculation) and critical windows (0-9, 10-14, and 70-90 days prior to ejaculation) on semen quality.
Seven databases were retrieved for original studies on the effects of six pollutants exposure for 90 days prior to ejaculation on semen quality. The search process does not limit the language and search date. We only included original studies that reported regression coefficients () with 95% confidence intervals (CIs). The and 95% CIs were pooled using the DerSimonian-Laird random effect models.
PM exposure was related with decreased total sperm number (10-14 lag days) and total motility (10-14, 70-90, and 0-90 lag days). PM exposure was related with reduced total sperm number (70-90 and 0-90 lag days) and total motility (0-90 lag days). NO exposure was related with reduced total sperm number (70-90 and 0-90 lag days). SO exposure was related with declined total motility (0-9, 10-14, 0-90 lag days) and total sperm number (0-90 lag days).
Air pollution affects semen quality making it necessary to limit exposure to air pollution for Chinese men. When implementing protective measures, it is necessary to consider the key period of sperm development.
空气污染可能会损害男性生育能力，但直到现在，空气污染是否会影响精液质量仍存在争议。
我们进行了一项荟萃分析，以探讨在整个窗口期（射精前 0-90 天）和关键窗口期（射精前 0-9、10-14 和 70-90 天）暴露于六种污染物对精液质量的潜在影响。
检索了七个数据库，以获取有关暴露于六种污染物（射精前 90 天）对精液质量影响的原始研究。搜索过程不受语言和搜索日期的限制。我们仅纳入了报告回归系数（β）及其 95%置信区间（CI）的原始研究。使用 DerSimonian-Laird 随机效应模型对β和 95%CI 进行汇总。
PM 暴露与总精子数减少（10-14 滞后天）和总活力降低（10-14、70-90 和 0-90 滞后天）相关。PM 暴露与总精子数减少（70-90 和 0-90 滞后天）和总活力降低（0-90 滞后天）相关。NO 暴露与总精子数减少（70-90 和 0-90 滞后天）相关。SO 暴露与总活力下降（0-9、10-14、0-90 滞后天）和总精子数减少（0-90 滞后天）相关。
空气污染会影响精液质量，因此有必要限制中国男性接触空气污染。在实施保护措施时，有必要考虑精子发育的关键时期。
