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胆肠吻合术与胆肠吻合术治疗胆总管囊肿切除术后胆道重建:系统评价和荟萃分析。

Biliary reconstruction after choledochal cyst resection: a systematic review and meta-analysis on hepaticojejunostomy vs hepaticoduodenostomy.

机构信息

Tecnológico de Monterrey, Escuela de Medicina y Ciencias de la Salud, Ave. Batallón San Patricio #112, San Pedro Garza García, Monterrey, Nuevo León, Mexico.

Tecnológico de Monterrey, Escuela de Ingeniería y Ciencias, Monterrey, Nuevo León, Mexico.

出版信息

Pediatr Surg Int. 2021 Oct;37(10):1313-1322. doi: 10.1007/s00383-021-04940-z. Epub 2021 Jun 11.

DOI:10.1007/s00383-021-04940-z
PMID:34115175
Abstract

Choledochal cysts are a rare pediatric biliary pathology. Excision of the extrahepatic cyst and restoration of biliary-enteric continuity through either hepaticoduodenostomy (HD) or Roux-en-Y hepaticojejunostomy (HJ) is the mainstay treatment. This study aims to determine if either method provides an advantage. Following PRISMA guidelines, a systematic review was conducted, identifying studies comparing hepaticojejunostomy to hepaticoduodenostomy in patients with choledochal cysts. Data were analyzed using Review Manager 5.3. Nine studies were included, operative time was shorter - 97.50 [- 172.31, - 22.69] p = 0.01 and bleeding reduced - 48.98 [- 88.25, - 9.71] p = 0.01 in HD. HD was associated with shorter length of stay 2.18 [- 3.87, - 0.50] p = 0.01 and similar cholangitis and reintervention rates. Time to a normal diet was similar between groups. Biliary reflux was seen more frequently in HD 19.14 [2.60, 140.63] p = 0.004. Complications such as leak and cholangitis were similar between groups. HD represents a viable alternative to HJ with various advantages such as shorter operative time, decreased bleeding and shorter length of hospital stay. Bile reflux remains a major limitation.Level of evidence IV.

摘要

胆总管囊肿是一种罕见的小儿胆系病理学疾病。切除肝外胆管囊肿并通过肝肠吻合术(HD)或 Roux-en-Y 肝肠吻合术(HJ)恢复胆肠连续性是主要的治疗方法。本研究旨在确定这两种方法是否具有优势。根据 PRISMA 指南,进行了系统评价,确定了比较胆管囊肿患者肝肠吻合术与肝肠吻合术的研究。使用 Review Manager 5.3 分析数据。共纳入 9 项研究,HD 的手术时间更短 [97.50(-172.31,-22.69),p=0.01],出血量更少 [-48.98(-88.25,-9.71),p=0.01]。HD 与较短的住院时间相关 [2.18(-3.87,-0.50),p=0.01],且胆系感染和再干预率相似。两组恢复正常饮食的时间相似。HD 中更频繁地出现胆汁反流 [19.14(2.60,140.63),p=0.004]。HD 和 HJ 的并发症如漏和胆系感染相似。HD 作为 HJ 的一种可行替代方法,具有多种优势,如手术时间更短、出血减少和住院时间更短。胆汁反流仍然是一个主要的局限性。证据等级为 IV 级。

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本文引用的文献

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Surg Endosc. 2020 May;34(5):2172-2177. doi: 10.1007/s00464-019-07004-5. Epub 2019 Jul 24.
2
Long-term outcomes of surgery for choledochal cysts: a single-institution study focusing on follow-up and late complications.胆总管囊肿手术的长期结果:一项聚焦随访和晚期并发症的单机构研究
Surg Today. 2018 Sep;48(9):835-840. doi: 10.1007/s00595-018-1660-9. Epub 2018 Apr 20.
3
胆总管囊肿切除术后的胰瘘和出血:二十年经验
Turk J Surg. 2024 Jun 28;40(2):104-110. doi: 10.47717/turkjsurg.2024.6354. eCollection 2024 Jun.
4
Biliary Reconstruction with Hepaticoduodenostomy Versus Hepaticojejunostomy After Choledochal Cyst Resection: A Narrative Review.胆总管囊肿切除术后肝十二指肠吻合术与肝空肠吻合术的胆道重建:一项叙述性综述
J Clin Med. 2024 Oct 31;13(21):6556. doi: 10.3390/jcm13216556.
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Outcome of Biliary-enteric Reconstruction with Hepaticoduodenostomy Following Choledochal Cyst Resection: A Prospective Study.肝肠吻合术治疗胆总管囊肿切除术后胆肠吻合口的结果:一项前瞻性研究。
Afr J Paediatr Surg. 2024 Jan 1;21(1):39-47. doi: 10.4103/ajps.ajps_43_23. Epub 2024 Jan 20.
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Pediatr Surg Int. 2013 Apr;29(4):317-26. doi: 10.1007/s00383-013-3266-z. Epub 2013 Jan 31.
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