University of Minnesota Medical School-Twin Cities.
Department of Dermatology, University of Minnesota, Minneapolis.
Dermatitis. 2022;33(5):332-336. doi: 10.1097/DER.0000000000000771. Epub 2022 Jun 11.
Aerosolized liquid (e-liquid) of electronic cigarettes can be toxic. Beyond the solvent (propylene glycol, vegetable glycerin) and nicotine, little is known about the liquid composition. Formaldehyde, a carcinogen and source of contact dermatitis, has been reported in the vaporized e-liquid, but no studies have assessed the actual e-liquid.
The aim of the study was to evaluate e-liquid products for the presence of formaldehyde.
Sixteen e-liquid products were purchased and analyzed for the release of formaldehyde using the chromotropic acid method of detection.
Of the 16 e-liquids purchased, 4 (25%) were positive for the presence of formaldehyde; 2 were flavored and 2 were nonflavored. All positive e-liquids were in pods or disposable electronic cigarette devices, and 2 were purchased from local vape shops. The average nicotine content in the positive e-liquids was 3.85% versus 4.03% in the negative e-liquids.
The e-liquid products contain toxic chemicals not declared on product labels, as shown in this study with 25.0% of e-liquids containing formaldehyde. All positive e-liquids were within pods or disposable devices. Continued analysis of e-liquids and increased product regulation are needed.
电子烟的雾化液体（电子液体）可能具有毒性。除了溶剂（丙二醇、植物甘油）和尼古丁之外，人们对液体的成分知之甚少。已在雾化的电子液体中报告了甲醛的存在，甲醛是一种致癌物质和接触性皮炎的根源，但尚无研究评估实际的电子液体。
本研究旨在评估电子液体产品中甲醛的存在情况。
购买了 16 种电子液体产品，并使用变色酸法检测来评估甲醛的释放情况。
在购买的 16 种电子液体中，有 4 种（25%）呈阳性，表明存在甲醛；其中 2 种为调味型，2 种为非调味型。所有呈阳性的电子液体都在烟弹或一次性电子烟设备中，其中 2 种是从当地的电子烟商店购买的。阳性电子液体的平均尼古丁含量为 3.85%，而阴性电子液体的尼古丁含量为 4.03%。
正如本研究所示，电子液体产品中含有未在产品标签上声明的有毒化学物质，25.0%的电子液体中含有甲醛。所有呈阳性的电子液体都在烟弹或一次性设备内。需要继续对电子液体进行分析，并加强产品监管。
