Unit of Lasers in Dermatology, Università Roma Tor Vergata, Rome, Italy.
Unit of Dermatology, Department of Health Sciences, Magna Graecia University, Catanzaro, Italy.
Photobiomodul Photomed Laser Surg. 2021 Sep;39(9):617-621. doi: 10.1089/photob.2020.4927. Epub 2021 May 25.
To evaluate the histological effects of a new 675-nm laser device on the skin. Innovative technologies based on physical principles have been proposed in recent years to improve the treatment of aging skin. Laser technology is currently being studied for its potential in skin care treatments. A new 675-nm laser device is being used for the treatment of hyperpigmentation, scars, and various types of wrinkles. A 42-year-old man underwent a 675-nm RedTouch laser session for the treatment of aging signs on the neck. Two 2.5-mm biopsies were taken from the treated area and the adjacent area untreated with the laser, 45 days after the procedure. Comparison of the immunohistochemistry findings and assessment of the collagen and elastin fibers were performed by a board-certified dermatopathologist. Skin biopsies revealed histological changes that comprised proliferation of new collagen fibers in the treated area, when compared to that in the untreated areas. Histological analysis suggests that the 675-nm laser has a potential role in stimulating collagen remodeling, with a significant increase in thin and new collagen fibers.
评估一种新型 675nm 激光设备对皮肤的组织学影响。近年来,基于物理原理的创新技术被提出来改善皮肤老化的治疗效果。激光技术目前正在被研究用于皮肤护理治疗。一种新型 675nm 激光设备被用于治疗色素沉着、疤痕和各种类型的皱纹。一名 42 岁男性因颈部老化迹象而接受了 675nm RedTouch 激光治疗。治疗后 45 天,在治疗区域和未用激光治疗的相邻区域分别取 2.5mm 活检。由经过认证的皮肤科病理学家进行免疫组织化学检查结果比较和胶原及弹力纤维评估。皮肤活检显示,与未治疗区域相比,治疗区域有新的胶原纤维增生。组织学分析表明,675nm 激光在刺激胶原重塑方面具有潜在作用,使细的和新的胶原纤维显著增加。
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