Coricciati Medical Group, Martano, Italy.
El.En. Group, Calenzano, Italy.
Skin Res Technol. 2023 Aug;29(8):e13434. doi: 10.1111/srt.13434.
Melasma is an acquired skin problem. It characterises sun-exposed areas, particularly on the face, with irregular borders and bilateral distribution. With this study, we want to strengthen the scientific literature regarding the use of a 675-nm laser device for the treatment of women and men with facial melasma pigmentary and vascular symptoms.
Eighteen patients were treated for facial melasma. A total of three sessions at 30-day intervals were performed with a 675-nm laser device. A five-point Global Aesthetic Improvement Scale was used to separately assess the improvement of the patient's skin 3 months after the last treatment (T1) compared to baseline (T0). The pain during treatment was measured using a Visual Analog Scale of 10 points. The non-ablative laser system used emits red light with a wavelength of 675 nm through a 13 × 13 mm scanning system.
At T , a consistent improvement in the pigmentary and vascular components was visible. This is always combined with a considerable reduction in vascular expression.
Our research shows that individuals with Fitzpatrick phototypes II to III can treat facial melasma with the 675-nm laser source system without risk. Due to its interaction with melanin, collagen and haemoglobin chromophores, as well as its excellent capacity to penetrate tissues with less heating, this system is promising in the treatment of pigmentary and vascular illnesses such as melasma. The great success of the technology we used came from the reduced levels of inflammation produced after the treatments and the low energy level implied.
黄褐斑是一种获得性皮肤问题。它的特征是在暴露于阳光的部位出现不规则边界和双侧分布的色素沉着。本研究旨在加强关于使用 675nm 激光设备治疗女性和男性面部黄褐斑色素性和血管症状的科学文献。
对 18 名面部黄褐斑患者进行了治疗。使用 675nm 激光设备进行了三次间隔 30 天的治疗。采用五点整体美学改善量表分别评估患者在最后一次治疗后 3 个月（T1）与基线（T0）相比皮肤改善情况。使用 10 分视觉模拟量表测量治疗期间的疼痛。非剥脱性激光系统发射波长为 675nm 的红光，通过 13×13mm 的扫描系统进行发射。
在 T 时，可见色素性和血管成分的一致改善。这总是伴随着血管表达的显著减少。
我们的研究表明，Fitzpatrick 光型 II 至 III 的个体可以使用 675nm 激光源系统安全地治疗面部黄褐斑。由于其与黑色素、胶原蛋白和血红蛋白色素的相互作用，以及其穿透组织的能力差、加热少，该系统在治疗色素性和血管性疾病如黄褐斑方面具有广阔的前景。我们使用的技术取得巨大成功的原因是治疗后炎症水平降低和能量水平较低。
Zotero 插件
