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临床流行病学中的关键概念:反应度,效度的纵向方面。

Key concepts in clinical epidemiology: Responsiveness, the longitudinal aspect of validity.

机构信息

Amsterdam UMC, Vrije Universiteit Amsterdam, Departement of Epidemiology and Data Science, Amsterdam Public Health research institute, De Boelelaan 1117, Amsterdam, The Netherlands.

Amsterdam UMC, Vrije Universiteit Amsterdam, Departement of Epidemiology and Data Science, Amsterdam Public Health research institute, De Boelelaan 1117, Amsterdam, The Netherlands.

出版信息

J Clin Epidemiol. 2021 Dec;140:159-162. doi: 10.1016/j.jclinepi.2021.06.002. Epub 2021 Jun 8.

DOI:10.1016/j.jclinepi.2021.06.002
PMID:34116141
Abstract

OBJECTIVES

Responsiveness is one of nine measurement properties that reflect the quality of outcome measurement instruments.

METHODS

In this article, we explain that responsiveness is considered longitudinal validity, which refers to the degree to which an instrument is able to measure change in the construct to be measured.

RESULTS

Responsiveness should be assessed in a longitudinal design, where hypotheses are tested about (1) the expected direction and magnitude of correlations between change scores on the instrument of interest and change scores of other instruments; (2) expected differences in change scores between different subgroups (i.e. known groups); or (3) the magnitude of the change in score that is expected on the construct of interest after a treatment with known efficacy.

CONCLUSION

Responsiveness cannot be proven, though, it is an ongoing process of testing hypotheses.

摘要

目的

反应度是反映结局测量工具质量的九个测量特性之一。

方法

本文将解释反应度被认为是纵向有效性,它是指仪器能够测量待测量结构变化的程度。

结果

反应度应该在纵向设计中进行评估,在该设计中,关于以下内容检验假设:(1)感兴趣的仪器的变化分数与其他仪器的变化分数之间相关性的预期方向和大小;(2)不同亚组(即已知组)之间变化分数的预期差异;或(3)在具有已知疗效的治疗后,预期在感兴趣的结构上的分数变化幅度。

结论

虽然无法证明反应度,但是它是一个不断检验假设的过程。

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