Molecular Biology Research Center, Systems Biology and Poisonings Institute, Baqiyatallah University of Medical Sciences, Tehran, Iran.
Communicable Diseases Institute, Mazandaran University of Medical Sciences, Sari, Iran.
J Wound Care. 2021 Jun 2;30(6):465-468. doi: 10.12968/jowc.2021.30.6.465.
This case report describes the progressive wound infection in the left thigh of a 34-year-old man due to an old landmine explosion. The infection developed into rapidly spreading skin and soft tissue necrotising infection, despite antifungal therapy and surgical debridement. The report provides evidence that spp. should be added to the list of mucoralean fungi that can cause severe necrotising infection. It also highlights the need for improved early diagnostic procedures and enhanced understanding of virulence factors that contribute to necrotising infection.
本病例报告描述了一名 34 岁男性因旧地雷爆炸导致左大腿进行性伤口感染。尽管进行了抗真菌治疗和手术清创,但感染仍发展为迅速扩散的皮肤和软组织坏死性感染。该报告提供了证据表明, spp. 应该被添加到能够引起严重坏死性感染的毛霉目真菌列表中。它还强调了需要改进早期诊断程序和增强对导致坏死性感染的毒力因子的理解。